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Application of Heart Function Echocardiographic Multi-Parameter Score (HF- EMPS) in Assessment of Response to the Guideline-recommended Treatments of Chronic Heart Failure (CHF)

Author: ZhaoLi
Tutor: YangJunHua
School: Suzhou University
Course: Internal Medicine
Keywords: Chronic heart failure (CHF) Echocardiography Cardiac function Score Treatment
CLC: R541.6
Type: Master's thesis
Year: 2011
Downloads: 16
Quote: 0
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Abstract


【Objective: Application heart function ultrasonic multi-parameter score (HF-EMPS) overall evaluation of patients with chronic heart failure (CHF), cardiac functional status, and treatment and prognosis evaluation. Methods: for chronic heart failure patients (CHF) 83 patients underwent echocardiography, HF-EMPS rating determination of BNP, New York Heart Association functional classification, to the AHA heart failure guidelines recommend standardized treatment, regular telephone follow-up and our hospital out-patient follow-up, respectively, at 6 months after the first visit and within 12 months of the review of ultrasound echocardiography. 1. Analysis of the relationship between the HF-EMPS plasma BNP, New York Heart Association functional classification. Analysis before and after treatment the HF-EMPS its composition changes in the parameters. (3) analysis of the follow-up period HF-EMPS its constituent parameters change in, CHF treatment effect, treatment outcome. 4. Application HF-EMPS evaluation of different causes, duration of treatment effect. 5. Logistic regression methods to analyze the parameters of the HF-EMPS its composition can affect the risk factors for sustained increases in BNP. 【Results】: 1.HF-EMPS values ??with the New York Heart Association functional classification higher and higher, significant differences between the different grading; and lgBNP ie plasma BNP levels were positively correlated (r = 0.43, P lt; 0.05). HF-2. Standardized treatment EMPS values ??and its component parameter values ??with increasing follow-up time is reduced. 6 months and 12 months of treatment echocardiography: HF-EMPS values ??and pulmonary artery pressure parameters are further reduced, and the difference was significant (P values ??lt; 0.05); parameters of valvular regurgitation, left ventricular systolic function and diastolic function parameters (E / e ') in the 6 months of treatment has been significantly decreased (P lt; 0.05); Although left ventricular remodeling parameters follow-up period to reduce the trend, but the differences were not statistically significant. Reconstruction to improve the group of patients with newly diagnosed left ventricular remodeling index was significantly less than the the hemodynamic improvement group and the non-improvement group, suggesting that a lesser degree of left ventricular remodeling in patients with CHF more likely to benefit from the short-term treatment. Different causes of CHF HF-EMPS values ??with increasing duration of treatment showed a decreasing trend, including peripartum cardiomyopathy, alcoholic cardiomyopathy HF-EMPS value decreases most obvious, heart disease, changes in the degree of expansionary minimum; negative correlation between the course of the disease in patients with CHF treatment effect. 5.HF-EMPS event group, arranged between the readmission group and death group showed an increasing trend; pulmonary artery pressure parameters in the death group and event group, readmission significant difference between the groups. Ventricular remodeling and pulmonary artery pressure increased BNP consistently higher than 400pg/ml strong risk factors, which was expressed as: P (1) = 1 / [1 e-(1.157 1.204PAP 1.207 left ventricular remodeling parameters )]. Conclusion: HF-the EMPS can be used for the assessment of the overall cardiac function in patients with chronic heart failure, to guide the treatment of patients with chronic heart failure, treatment evaluation and prognosis. Hemodynamic parameters can improve early in the course of treatment in patients with chronic heart failure, ventricular remodeling parameters to improve the long-term treatment is required. Left ventricular remodeling in severe pulmonary artery pressure continued to increase as a strong risk factor for adverse cardiovascular events in patients with chronic heart failure.

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CLC: > Medicine, health > Internal Medicine > Heart, blood vessels ( circulatory ) disease > Heart disease > Blood circulation failure
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