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Traditional fracture fixation materials are usually made ??of titanium , but difficult to overcome the shortcomings of metallic materials . Biodegradable materials is currently the most promising fracture fixation material degradation resistance and mechanical strength are the key factors that affect fracture effects and postoperative complications . Currently , our department has with the Changchun Institute of Applied Chemistry jointly developed a new PLLA micro- absorbable plates and screws . In this study, dogs with bilateral mandibular fracture model , parallel absorption splint fixation . Postoperative 1,2,3,6,12 and 15 months , respectively, the animals were sacrificed to remove the splint for substantially and electron microscopy , measuring the quality of the splint , the molecular weight and the maximum bending strength , the absorption rate is calculated in each group , degradation rate , and the maximum bending intensity decay rate , compared with similar products . The results show that : the splint implanted after two months faster degradation rate gradually slowed down from three months to start ; mechanical strength slower decay rate of the previous three months , from the first four months , began to significantly increase fast. The degradation rate change in advance to the absorption rate changes, early degradation faster than the mechanical strength of decay rate . Conclusion : In this lab , we get this biodegradability and mechanical strength of the independent intellectual property rights of PLLA micro splint valuable scientific data to prove that the degradation rate of the splint is more reasonable , relatively good mechanical strength , has basically met the fixed function craniofacial fractures . But compared to similar products abroad , the initial strength of the plywood there to be improved , still slightly faster rate of decay of the early mechanical . Then put forward the ideal indicators of degradation rate and mechanical strength , and pointed out the direction for the further improvement of the material , which laid the foundation for the localization of new material as soon as possible into the clinical application .
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