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Objective: Tissue Doppler imaging (Doppler tissue imaging) technical evaluation of diabetes patients and their consolidation in patients with hypertension cardiac structure and cardiac systolic and diastolic function changes, designed to reveal the impact of diabetes and hypertension in patients with myocardial. Method: 1. Choose as the experimental group, type 2 diabetes (Diabetes mellitus, DM) 103 patients divided into two subgroups: patients with normal blood pressure, diabetes subgroup (DM-NP) 50 patients with hypertension diabetes Asia group (DM-HP) 53 cases. Selected 50 normal subjects were selected as the control group (NC). 2. Applications the GE Vivid7 ultrasonic diagnostic apparatus, line of conventional two-dimensional ultrasound echocardiography the measurement routine cardiac data including left atrium inside diameter (LA), interventricular septum thickness (IVS), left ventricular posterior wall thickness (LVPW), ejection fraction ( EF%), calculated left ventricular mass index (LVMI). Transferred to the TVI conditions, respectively measuring the left ventricular wall, after the interval, six sites of the posterior wall of the former interval and anterior wall of the mitral ring systolic peak velocity (Sa), early diastolic peak velocity ( Ea), late diastolic peak movement speed (Aa), each part of the measurement of three cardiac cycles mean value, and calculated diastolic early and late peak velocity ratio (Ea / Aa) and Tei index. Results: 1. Transthoracic two-dimensional measurement values: a. Diabetes group compared with the measured values ??of the left ventricle of the control group, two-dimensional: two groups measured LA, IVS, LVPW, EF% had no statistically significant. LVMI higher than the control group, p lt; 0.05. b comparison: the subgroup of patients with normal blood pressure, diabetes and hypertension, diabetes subgroup of patients with left ventricular two-dimensional measurement values ??with hypertension diabetes subgroup (DM-HP) IVS, LVPW and LVMI than those with normal blood pressure diabetes subgroup ( DM-NP) increased, p lt; 0.05. LA EF% between the two was not statistically significant between the Mitral ring you point measurements. Within each group comparison: the experimental group, two subgroups of the experimental group and the control group mitral annular Doppler velocity measured values, the organization of the six sites, each group sidewall wall, posterior wall motion speed is greater than the interval, anterior maximum sidewall movement speed. a diabetes group and the control group mitral ring you point measured values ??compare: diabetes group overall movement speed mitral annular Ea, Ea / Aa than in the control group to reduce, p lt; 0.05. Diabetes group after the interval reduced sidewall anterior, inferior, anterior septum and posterior wall of the mitral ring Ea compared with the control group, p-lt; 0.05. Elevated sidewall mitral annulus Aa compared with the control group, p lt; 0.05. b subgroup of normal blood pressure, diabetes and high blood pressure diabetes subgroup mitral ring locus measured value comparison: no significant difference in the overall speed of movement of the mitral annulus in the subgroup of normal blood pressure, diabetes and high blood pressure diabetes subgroups. The interval Aa than normal blood pressure, diabetes subgroup reduce hypertensive diabetic subgroup ago, p lt; 0.05. Tissue Doppler systolic and diastolic indicators measured value comparison: the systolic function parameters between groups comparison: the diabetic group and the control group, hypertension diabetic subgroups compared with the normotensive diabetic subgroup Sa measured values ??were not statistically different (p gt; 0.05), hypertensive diabetic subgroup Sa than the other two groups to reduce the trend. Diastolic function parameters between groups comparison: the Ea measured values ??of the diabetic group than the control group to reduce, p lt; 0.05; Aa measured value is higher than the control group, but there was no statistically significant difference p gt; 0.05; Ea / Aa ratio compared with the control group to reduce, p lt; 0.01. Hypertensive diabetic subgroup the Ea measured values, Aa measured values ??and Ea / Aa ratio with normal blood pressure, diabetes subgroup no significant difference, p gt; 0.05 4.Tei index comparison: the diabetic group compared with control group Tei index increased no significant differences were 0.58 ± 0.13 and 0.34 ± 0.05, p lt; 0.01 Central Asia group, diabetes group, p gt; 0.05 5. correlation analysis: diabetes course and Ea / Aa correlation analysis show a negative correlation course and Ea / Aa r = -0.655, p lt; 0.05 (bilateral); level of glycosylated hemoglobin (GHb) and Ea / Aa analysis show a negative correlation, the GHb and Ea / Aa r = -0.621, p lt; 0.05 (two-sided). Conclusion: 1 diabetics have a higher body mass index and blood lipid levels, presence of hypertension or not did not show a clear influence. Caused by hypertension cardiac afterload increase left ventricular hypertrophy. Hyperglycemia diastolic function could be worse than in the blood pressure. 4 level of glycosylated hemoglobin (GHb) analysis showed a negative correlation with Ea / Aa course of patients with diabetes and Ea / Aa analysis showed a negative correlation. Diabetic patients with early diastolic dysfunction, systolic dysfunction did not occur. At the same time, the high blood pressure can aggravate existing diabetes myocardial damage.
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