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Prescription and sulfasalazine in the treatment of rheumatoid Ⅰ clinical study of 80 patients with ankylosing spondylitis

Author: MaJun
Tutor: YangDeCai
School: Hubei College of Traditional Chinese Medicine
Course: Traditional Chinese Medicine
Keywords: Ankylosing Spondylitis Treatment TCM therapy Rheumatism I Recipe Clinical Research
CLC: R593.23
Type: Master's thesis
Year: 2007
Downloads: 67
Quote: 0
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Abstract


Ankylosing spondylitis (ankylosing spondylitis, AS) is a chronic inflammation of the axis joints and tendon ligament bone attachment points based systemic disease, inflammatory low back pain, tendon inflammation, peripheral arthritis and extra-articular manifestations of characteristics. Mainly involving the sacroiliac joint, spine and limbs, joints, the performance of the joints and tissues around joints, ligaments, calcification of the intervertebral disc, intervertebral joints and limbs synovial hyperplasia, and ultimately the development of bony ankylosis. Modern medical understanding of the etiology of this disease is unclear, the lack of clinical specificity, resulting in efficacy Nanjinrenyi. For the past two years, under the guidance of my mentor Professor Yang Decai use based on years of clinical experience, he summed up the rheumatoid Ⅰ Prescription and sulfasalazine treatment of 80 patients with AS, in certain clinical effect. Our analysis of the clinical data, summed up the kidney yang deficiency, cold resistance network is the main etiology and pathogenesis of AS, kidney yang, dampness Tongluo pain \AS is the name of one of modern medicine, and their clinical performance, belonging to the motherland medicine \TCM classical medical disease clearly documented renal Bi \has a very important guiding significance for the treatment of AS on later. Modern physician etiology and pathogenesis of AS, diagnosis and treatment carried out a lot of useful work, has a very important role in medical research to enrich and develop the AS. But the current study is also significant disorder, lack of uniform understanding and standards, has brought a lot of questions and challenges to the efficacy and safety of AS TCM diagnosis and treatment, is not conducive to the TCM in standardization, standardization and internationalization of development. I clinical study part, rheumatoid No. Ⅰ side treatment of AS patients, the clinical efficacy conduct evaluation, in the international arena is more general purpose of evaluation standard base, combined with Professor mentor Yangde Cai's long-term clinical practice, the use of internationally recognized efficacy assessment methods to carry out evaluation of Chinese medicine, language internationalization. We are trying to promote clinical focus on evidence from the emphasis on experience, experience in medical shift to evidence-based medicine, the AS of Medicine Clinical Research more standardized, standardization, Chinese and Western medicine to reach a consensus on the treatment of AS. 80 AS patients before and after treatment of symptoms, signs, and laboratory indicators of comparative analysis, show that the party to improve the symptoms of patients with AS, signs, laboratory parameters have a good effect. The the side treatment group efficacy analysis: clinical remission rate was 10.0%, effective rate of 20.0%, the effective rate was 50.0%, ineffective rate was 20.0%, the total effective rate was 80.0%; significantly better than the control group, 50% (P <0.05), and found to improve the patient's clinical symptoms, improve joint function, immune regulation, improve the body's functional status and quality of life aspects better, proved rheumatoid Ⅰ side ankylosing spondylitis \deficiency, cold resistance network \In short, rheumatoid Ⅰ can only improve AS patients with clinical symptoms, signs and laboratory tests indicators achieved encouraging results in clinical practice, but the mechanism of action of the party still needs further research.

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CLC: > Medicine, health > Internal Medicine > Systemic disease > Autoimmune diseases > Autoimmune diseases, connective tissue disease > Ankylosing spondylitis
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