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Application Study of Diffusion Tensor Imaging in Both Normal Optic Radiation and Abnormal Optic Radiation Induced by Intracranial Neoplasms

Author: SunZuo
Tutor: XiaoXinLan
School: Nanchang University
Course: Medical Imaging and Nuclear Medicine
Keywords: Optic radiation FA values MD value Tumor Diffusion tensor imaging Diffusion tensor imaging
CLC: R445.2
Type: Master's thesis
Year: 2007
Downloads: 115
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Abstract


Chapter 1 normal adult optic radiation of magnetic resonance diffusion tensor imaging study Objective: To analyze the normal adult optic radiation anisotropy and increases with age anisotropic changes in the optic radiation law. Materials and Methods: Measuring 60 normal volunteers (29 men and 31 women, aged 24-66 years, mean age 42.8 years) optic radiation FA and MD values. Results: FA values ??in normal adult optic radiation were left 0.517 ± 0.023, the right side 0.514 ± 0.021; MD values ??for the left (0.743 ± 0.024) × 10 -3 the mm 2 / s, the right side of (0.740 ± 0.025) × 10 -3 mm 2 / s, bilateral There was no significant difference (P gt; 0.05 ). Analyze the correlation between the optic radiation FA values ??and MD values ??with age, FA values ??show a downward trend with increasing age, but no significant correlation between MD values ??increased with increasing age, MD with age significant positive correlation (r = 0.281, p = 0.029). Conclusion: FA values ??quantitative analysis of the degree of anisotropy of the optic radiation. With increasing age, FA values ??decreased MD values ??tended to increase. Chapter 2 magnetic resonance diffusion tensor imaging tumors of the optic radiation Objective: To evaluate magnetic resonance diffusion tensor imaging tumor of the optic radiation optic radiation fibers caused by abnormal changes in value. Materials and Methods: 33 patients (18 male, 15 female, age 35 8 1 year old, average 54.1 years), optic radiation cancer patients diffusion tensor imaging, on the one hand, the obtained data diffusion tensor imaging, FA maps, DEC Figure and DTT Figure observe the different lesions caused by the changes of the optic radiation fibers. On the other hand, abnormal lesions around the optic radiation and normal optic radiation values ??of FA and MD values ??measurement, quantitative analysis of the the abnormal optic radiation anisotropy change. Results: abnormal changes in the optic radiation fibers are divided into four types: the destruction of 18 cases of infiltration; destruction shift five cases; the infiltration shift four cases; shift in 6 cases. Quantitative analysis can be found: 1 ipsilateral optic radiation FA values ??significantly lower than the contralateral optic radiation area, there is a significant difference between the two (P lt; 0.01); (2) ipsilateral optic radiation MD was significantly higher than the contralateral optic radiation, between the two, there is a significant difference (P lt; 0.01); (3) three tumor ipsilateral optic radiation FA values ??in comparison the metastases group ipsilateral optic radiation FA values ??below meningioma group, two there is a significant difference between (P lt; 0.05); ④ three groups of tumor ipsilateral optic radiation MD value comparison, the metastases group ipsilateral optic radiation MD value glioma group, meningioma group there was a significant difference (P lt; 0.05). Conclusion: a magnetic resonance diffusion tensor imaging can show abnormal changes of the optic radiation caused by the tumor of the optic radiation, diffusion tensor fiber tracking stereoscopic display the relationship between the tumor and the optic radiation fibers, is conducive to tumor surgery program the development and prognosis of patients with forecasts. 2, FA values ??and MD values ??can be used for quantitative analysis of the tumor caused by the fiber bundle of optic radiation dispersion characteristic changes.

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CLC: > Medicine, health > Clinical > Diagnostics > Diagnostic Imaging > Magnetic resonance imaging
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