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A Pilot Study on the Breast Caner Risk Assessment Model of the Women in Beijing and Guangzhou

Author: ZhaoZuoLing
Tutor: PanXiaoPing
School: Sichuan University
Course: Epidemiology and Biostatistics,
Keywords: Breast Cancer Risk Factors logistic regression model Discriminant Analysis Breast cancer risk assessment model Gail model
CLC: R737.9
Type: Master's thesis
Year: 2007
Downloads: 216
Quote: 1
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Objective screening Beijing , Guangzhou, the two women with breast cancer risk factors ; formulation suitable for China 's breast cancer risk assessment model to explore its evaluation criteria ; comparing the similarities and differences between the model and the Gail model . By logistic regression screening method for breast cancer risk factors ; will filter out all at once streamlined factors into logistic regression model analysis, breast cancer risk assessment model ; validate the use of conditional logistic regression ; through discriminant analysis and evaluation model ; by calculating the area under the ROC curve comparing the model and the Gail model diagnostic performance and look for breast cancer using the ROC curve low, medium and high risk appropriate cut-off point . The results of this study showed that women with breast cancer risk factors may affect the more prominent are: a history of menopause , a history of abortion , contraception and drug history , family history of breast cancer , negative emotions, adverse events , poor emotional regulation , labor-intensive age. Risk factor screening in established based on risk assessment model , it is recommended to predict probability value P ≤ 0.29 judged as low risk populations , predicted probability value P ≥ 0.58 judged as high-risk populations , 0.29 < predicted probability value P <0.58 sentenced is in danger of crowd. Conclusions focus on prevention of breast cancer , the risk factors should be combined to carry out active and effective control measures. This study was breast cancer risk assessment model can be used for breast cancer screening high-risk populations . However, this study model or Gail model is just an initial self- assessment tool , in the application of these tools, you should consult professional advice , consider the test 's other physiological and pathological features .

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