Dissertation > Excellent graduate degree dissertation topics show

Study of Epidemiological Characteristics and Risk Factors of Coronary Artery Lesion of Admitted Children with Kawasaki Disease

Author: LiJun
Tutor: LiYaRui
School: Shanxi Medical
Course: Pediatrics
Keywords: Kawasaki disease Epidemiology coronary artery lesion risk factors
CLC: R725.4
Type: Master's thesis
Year: 2007
Downloads: 63
Quote: 0
Read: Download Dissertation


Objective To describe the epidemiological and clinical characteristics of KD.To investigate the risk factors on children with coronary artery lesion(CAL)secondary to Kawasaki disease (KD).Method Medical record with a KD diagnosis among patients<18 years of age in four hospitals(Shanxi Province Children’s Hospital,the First People’s Hospital of Jinzhong,the Third People’s Hospital of Datong and Yuncheng Central Hospital)from January 2000 to December 2004,which lie in central,north and south region of Shanxi province separately,were reviewed.Relative information about patients were filled in the unified questionnaire forms and analyzed with the software of SPSS11.5.All cases with or without CAL were analyzed by case-control study,and Logistic regression analysis for 15 influence factors of CAL was made.Results(1)During the study period 487 hospitalizations associated with KD were recorded in the four hospitals of Shanxi province.There are 73 cases in 2000,80 cases in 2001, 107 cases in 2002,87 cases in 2003,140 cases in 2004.The age onset ranged from 54 days to 16 years of age;the age peak was between 1 and 2 years old,that is,the second year after birth. 425(87.3%)occurred among children<5 years of age,230(47.2%)occurred among children<2 years of age.The male-to-female ratio was 1.74:1.331(68%)are classic Kawasaki disease; 156(32%)are atypical Kawasaki disease.The disease occurred more frequently in summer and winter and less frequently in autumn.The peak of onset between male and female is discordant: the peak for male lied in May and June(between spring and summer);while the peak for female lied in December and January(winter).The nadir of onset between male and female is coincide, which lied in April and October.458(94%)patients received the examination of ultrasound cardiogram(UCG)within 1 month after the onset.The incidence rate of CAL was 35.6%,the incidence rate of coronary artery aneurysms(CAA,≥4mm in diameter)was 7.4%,the incidence rate of giant coronary artery aneurysms(GCAA,≥8mm in diameter)was 0.66%.No death case was reported among hospitalized children.The recurrence rate was 2.3%.(2)univariate analysis indicated that the fever duration before hospitalization,the total fever duration,platelet(PLT), erythrocyte sedimentation rate(ESR),C-reactive protein(CRP)was closely associated with CAL secondary to KD(P<0.05 or P<0.01).Multivariate Logistic regression analysis indicated that age<1 year old,the total fever duration(>10days)and elevated CRP were independently correlated with CAL secondary to KD.Conclusion(1)Cases of KD are increasing year by year.The age and gender distribution are similar with those in previous reports,but the seasonal distribution is different.The incidence rate of CAL is higher,while the incidence rate of CAA is lower.The recurrence rate is low.(2) age<1 year old,the total fever duration(>10days)and elevated CRP are the high-risk factors of CAL in KD.

Related Dissertations

  1. Research and Analysis of Postcholecystectomy Diarrhoea (PCD) in Chronic Calculous Cholecystitis,R657.4
  2. The Studies and Establishment of Ready-mixed Concrete Information-guided Price on the Basis of Risk Analysis,F407.92
  3. The Empirical Research of the Important Factors of the Financial Risks of Chinese A-share Construction Enterprises Market,F426.92
  4. Molecular Epidemiological Analysis of Duck Hepatitis B Virus in Cherry Valley Duck in Henan Province and Anti-duck Hepatitis B Virus Activities of FNC in Vivo,S858.32
  5. Epidemiology and Prevention of Exopalamon Carincauda Infected with White Spot Syndrome Virus Within Jiangsu,S945
  6. Molecular Epidemiology about White Spot Syndrome in Jiangsu Province,S945.1
  7. Research on Relationship between Different TCM Dialectical Type and Associate with Sex Hormones and Risk Factors of Cardiovascular Disease in Perimenopausal Women of Hypertension,R259
  8. Investigation of Epidemiology of Porcine Circoviruses in JinHua of ZheJiang Province,S858.28
  9. Environmental Lead Exposure Among Preschool Children in Hefei, China: Blood Lead Level and Risk Factors,R179
  10. The Analysis of the Disease Constituent Ratio in 1130 Inpatients of the Department of Nephrology,R692
  11. Analysis of the Risk Factors Affecting Kidney Dysfunction Among Hospitalized Patients with Chronic Kidney Disease (an Analysis of 348 Cases),R692
  12. Analysis of Hand-foot-mouth Disease Prevalence and Influencing Factors in High Risk Group in Hefei City,R725.1
  13. Epidemiological Investigations and Studies of Highly Pathogenic Avian Influenza (H5N1) among Population with Different Occupations and Natural Environment in Fuyang,R511.7
  14. Heterogeneity and Meta Analysis of the Essential Hypertension Risk Assessments,R544.1
  15. Differential Diagnosis Significance in Patients with Chest Tightness Chest Pain and Analysis for the Risk Factors of Airflow Limitation,R54
  16. Clinical Study on Decompensation in Liver Cirrhosis and Establishment of Relevant Network Database,R575.2
  17. Risk Factors of Early Onset Type 2 Diabetes with Non-alcoholic Fatty Liver Disease,R587.1
  18. Clinical Epidemiological Survey and Analysis on Cholelithiasis in Zunyi Region,R657.4
  19. Research on Assessment of Risk of Strategy and Comprehensive Evaluation of Risk Management of Strategy,F272
  20. About Sports Injury Epidemiologycal Investigation and Analysis of Students on the College Entrance Examination in Shandong Province,G633.96
  21. A Retrospective Epidemiology Study of Comorbidities in Patients with Psoriasis,R758.63

CLC: > Medicine, health > Pediatrics > Children within the science > Pediatric cardiac and vascular disease
© 2012 www.DissertationTopic.Net  Mobile