|
Li Xue Kang soft capsules prescription for the clinical treatment of high cholesterol and atherosclerosis effective experience side , Fang rhubarb , Panax, ox bile powder shamisen components of Chinese medicine , has been in clinical applications based pills . Attending the function as meridians broken silt, blood and blood circulation . Mainly used for the treatment of hyperlipidemia , but because a large dose , inconvenient to carry , clinical application is limited. For the convenience of the patient , to improve its quality and efficacy of our group for its preparation , and quality standards for research and improvement of the system in order to produce good results. Preparation technology include: extraction process, ginsenoside Rg 1 content of evaluation index, high performance liquid chromatography - evaporative light scattering detection (HPLC) were measured, using orthogonal optimum extraction ; contents molding processes to soft capsule content sedimentation volume ratio , mobility , etc., as re- dispersibility evaluation index , a method using single factor and the amount of materials required for screening ; capsule technology of the skin to the viscosity , disintegration time as the evaluation index , select the appropriate sac Picchi the process parameters. Quality standard , the establishment of preparations ginsenosides Rg1 past the determination method, a preparation of rhubarb , Panax, ox bile powder TLC method ; and preparations for the general quality checks. The results show that the formulation preparation process is reasonable, feasible , stable quality , controllable , and has broad application prospects.
|