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Clinical Study on Protecting Stomach Decoction on Protection of Gastric Mucosa Injury

Author: MeiQiong
Tutor: GanAiPing
School: Hubei University of Chinese Medicine
Course: Chinese medical science
Keywords: Protecting stomach soup Gastric mucosal injury Erosivegastritis safety action Traditional Chinese medicine compound
CLC: R259
Type: Master's thesis
Year: 2013
Downloads: 60
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Abstract


Objective：Through clinical observation of protecting stomach soup against NSA-ID-induced (aspirin) gastric mucosal injury treatment and prevention，To un-derstand the clinical curative effect of traditional Chinese medicine compoundprotecting stomach Decoction in the treatment of gastric mucosal injury，Fur-ther observation of replenishing qi to invigorate the spleen，clearing heat andapplication of protecting stomach treatment in gastric mucosal injury in.For p-atients taking nonsteroidal anti-inflammatory drugs for cardiovascular and cer-ebrovascular diseases for traditional Chinese medicine of gastric mucosal prot-ective agent effective.Methods：Methods the clinical observation，Case selection digestion Departmentof internal medicine expert outpatient service were from Hubei ProvincialTraditional Chinese Medical Hospital2011.6-2012.6professor Gan Aiping，All the patients have no stomach disease history, and nearly three monthsbecause of cardiovascular and cerebrovascular diseases, taking aspirin,Clinical symptom of TCM to stomach pain, bloating, belching, acidregurgitation, heartburn and stomach syndrome, Clinical syndromedifferentiation of spleen deficiency stomach heat type, and55cases werediagnosed by endoscopy in patients with erosive gastritis,55patients weredivided randomly into treatment group and control group，The treatment group of30cases，25cases in the control group. The treatment group were treatedwith protecting stomach Decoction， The whole Party composed ofginseng30g，Poria15g，Atractylodes15g，radix10g，lily15g，Fructus aurantiiFructus Amomi10g, cuttlefish bone15g Rhizoma Bletillae20g，Fritillariathunbergii15g. Three seven powder，fried Puhuang with hemorrhage plus，withconstipation，with madder，Polygonum cuspidatum. Protecting stomach soup1dose daily，Shuijianbi，each time150mL，daily2times，After half an houror an hour.Take3months in a row.The control group was treated withranitidine hydrochloride capsules，1capsules each tim（e0.15grams），2timesa day，Yu Qingchen and bedtime. Take3months in a row. According to theState Food and Drug Administration promulgated in2002.“Guiding principleof clinical research on new drugs of traditional Chinese Medicine”The criteriaof efficacy evaluation，Changes of the gastric mucosa tissue changes ofclinical symptoms and endoscopic studies were observed before and aftertreatment，evaluate the efficacy，divided into cured, markedly effective,improved and invalid four curative effect standard.Compared with ranitidine.And further observation cases effective treatment group (28cases) to continueprotecting stomach soup while taking aspirin, Each time1grains (100mg)，1time a day after dinner service，continuous take1months, To observe theprotective effect of protecting stomach Decoction on gastric mucosa.Result：①Symptomatic efficacy of Chinese Medicine：The treatment group of30cases，17cases were recovery，6cases markedly effective，effective5cases，invalid in2cases，The total effective rate was93.34%；the controlgroup of25cases，10cases were recovery，In4cases，effective4cases，invalid7cases，the total efficiency of72%. Through statistical analysis，therewere significant differences between two groups（P<0.05）.Tip protectingstomach decoction can significantly improve the clinical symptoms of patients with erosive gastritis，And better than ranitidine.②Gastroscope efficacy: treatment group of30cases，6cases wererecovery，12cases markedly effective，effective8cases, invalid in4cases,The total effective rate was86.67%；the control group of25cases，5caseswere recovery，9cases markedly effective，effective2cases，invalid in9cases，The total efficiency of64%.Through statistical analysis, there weresignificant differences between two groups（P>0.05）.Tip protecting stomachdecoction treatment group and Western medicine ranitidine control groupunder microscope gastric mucosal healing rate had significant difference.③Protecting stomach soup and aspirin combined with protective effecton gastric mucosa：28cases of TCM symptom，protecting stomach soup andaspirin plus a month，Only3patients had obvious discomfort，25patients canybe affected by aspirin.That protecting stomach soup can stop aspirin ongastric mucosal damage，the protection of gastric mucosa.Conclution：Protecting stomach soup treatment by drugs (aspirin) gastritis spleenstomach erosion caused by，improve the clinical symptoms of traditionalChinese Medicine. The gastric mucosal damage can be repaired，And thecurative effect is better than that of ranitidine；Protecting stomach soup andaspirin combination can protect the gastric mucosa，Inhibition of aspirin ongastric mucosal injury. Effective Chinese herbal compound for the protectionof gastric mucosa in patients taking nonsteroidal anti-inflammatory drugs forcardiovascular and cerebrovascular diseases.

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