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Objective To investigate the non-acute myocardial infarction in type 2 diabetes mellitus (T2DM) patients with serum cardiac troponin T (cTnT) increases the clinical significance of cardiovascular complications of type 2 diabetes prevention, early diagnosis and treatment to provide new ideas. Methods According to 24-hour urinary albumin excretion rate selection T2DM patients 180 cases, the subjects were excluded nearly three months of acute myocardial infarction, autoimmune diseases, blood diseases, thyroid disease, severe infection, rheumatic heart disease, primary cardiomyopathy, primary kidney disease, severe liver disease. 1st serum cTnT greater than normal in patients with continuous review of ECG, cTnT, excluded groups into the cases of acute myocardial infarction. Combined with diabetic nephropathy Mogensen staging criteria are included in the study into three groups: urinary albumin lt; 30mg / D group (A group) 60 cases; urinary albumin is between 30 ~ 300mg / D group (B group) 60 cases; urinary albumin gt; 300mg / D or Scr higher than the reference value (C group) 60 cases. Gender composition among the three groups had no significant difference. Divided according to the value of cTnT cTnT cTnT positive group and negative group. Determination of T2DM patients cTnT, random blood glucose (RBG), fructosamine (FA), glycosylated hemoglobin (HbA1C), liver and kidney function, blood lipids, C-reactive protein (CRP). Follow-up 120 days, observed in patients with cardiovascular events and death events and to analyze its relationship with cTnT. Results (1) 180 cases of elevated cTnT 25 cases of patients with T2DM, including urinary albumin less than 30mg / D group (A group, 60 cases) cTnT elevated one case; urinary albumin between 30-300mg / D group (B group, 60 cases) cTnT elevated four cases; urinary albumin greater than 300mg / D or Scr higher than the reference value (C group, 60 cases) cTnT elevated in 20 cases. (2) cTnT 25 patients with elevated cardiovascular events occurred in 16 cases, 8 deaths, seven patients died of cardiovascular events; cTnT normal 155 cases of cardiovascular events occurred in 6 cases, 4 deaths, of which 1 died cardiovascular events, the difference was statistically significant (P lt; 0.01). (3) cTnT positive group and negative group: TG, TC, LDL-c, FA, HbA1c were compared no significant difference; cTnT positive group CRP levels were significantly higher cTnT negative group (P lt; 0.05); Hb levels cTnT positive group was significantly lower than cTnT negative group (P lt; 0.01), ALB cTnT levels were also significantly lower than the negative group (P lt; 0.05); cTnT positive patients, mostly elderly patients, and cTnT-negative group, Age difference was statistically significant (P lt; 0.01). Conclusions (1) With the progress of diabetic nephropathy, cTnT increased positive rate increases. (2) type 2 diabetic patients with elevated levels of serum cTnT cardiac microvascular disease induced myocardial injury related mortality of patients and can predict the incidence of cardiovascular events. (3) having high levels of cardiovascular risk in elderly patients, tight glycemic control alone can not effectively reduce the risk of major vascular events.
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