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Guidance of Carbon Nanoparticles Tracer in Advanced Gastric Cancer Lymphadenectomy

Author: GongXiMing
Tutor: FuXiaoGuang
School: Liaoning Medical
Course: Surgery
Keywords: Gastric cancer Advanced Carbon nanoparticles tracer Lymphadenectomy
CLC: R735.2
Type: Master's thesis
Year: 2013
Downloads: 10
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Abstract


ObjectiveTo study the clinical applied value of carbon nanoparticles tracer used toguide the advanced gastric cancer lymphadenectomy.Methods84cases of advanced distal gastric cancer were randomly divided into twogroups: a control group and tracer group. Two groups of patients were all gotthe D2-type radical surgery from the same operative group, who have richclinical experience in the surgery. The same person as the main operator, whowas responsible for detecting the intraoperative lymph nodes, reporting thegroup, the number of detected and whether dyed black, the postoperativespecimens by the person responsible for looking, grouping, counting all thelymph nodes, and indicate whether dyed black, after that, sent every packet forpathological examination. Use statistical software to process and analyze thedata collected, the differences were analyzed using independent samples t-test and X2test, tested significant differences in each group and compared twogroups of patients with lymph node finally seized.Results84cases of distal gastric cancer patients were all got the D2-type radicalsurgery from the same operative group, in which the control group seized734lymph nodes, each patient’s quantity of seizure was17.98±2.90grain, and thetracer group seized1091lymph nodes, the average case seized26.78±4.31grains. The latter’s quantity of seizure is significantly higher than the former’s (P＜0.05), the average lymph nodes which resected in D1(16.24±3.80) andD2(11.80±3.66) are higher in the tracer group than that in the control group(9.72±2.42and9.03±2.56). The total black-stained ratio of lymph node was(50.14℅), with D1(51.42℅) which was higher than D2(48.36℅) in the tracergroup. The positive rate of lymph node was higher in black-stained lymph nodeof tracer group (18.28℅) than in unstained lymph node of tracer group (6.43℅)and control group (9.26℅).ConclusionIt significantly increased the lymph nodes (including positive metastasis)of the seized amount in the lymphadenectomy of carbon nanoparticles tracerused to guide the advanced gastric cancer.

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CLC: > Medicine, health > Oncology > Gastrointestinal Cancer > Gastric neoplasms
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