Dissertation > Excellent graduate degree dissertation topics show

Study of Cyclodextrin Host-Guest Interaction by Spectroscopic Methods

Author: YuHengDa
Tutor: GuoXuHong
School: East China University of Science and Technology
Course: Chemical processes
Keywords: β-CD host-guest interaction fluorescence spectrometry rheology UV-Vis spectrometry
CLC: O636.1
Type: Master's thesis
Year: 2012
Downloads: 85
Quote: 0
Read: Download Dissertation

Abstract


In recent years, cyclodextrins (CDs) and their derivatives are widely used in the fields of food, drugs, environment protection and so on because of the excellent property of inclusion.In this thesis,β-CD and dansyl group substituted poly(acrylic acid) (PAAβ-CDen and PAADSen) were synthesized. The association constants between a variety of CDs and dansyl amide(DNSA) or PAADSen were determined by steady-state fluorescence spectroscopy. Polymer netwotks based on self-assembly of PAAβ-CDen and PAADSen were bulit and characterized by rheological and UV-Vis methods.(1)The synthesis of PAAβ-CDen can be divided into three steps. Firstly, monosulfonatedβ-cyclodextrin (β-CD-6-OTs) was obtained from the reaction bwtweenβ-CD and p-toluenesulfonyl chloride. Secondly, monoaminoβ-CD (β-CD-6-EDA) was obtained from the reaction betweenβ-CD-6-OTs and ethylenediamine. At last,β-CD-6-EDA was grafted onto PAA to get PAAβ-CDen. As for PAADSen, similar procedure was followed:firstly monoamino product of dansyl chloride was synthesiszed with dansyl chloride and ethylenediamine and then the monoamino product was grafted onto PAA to get PAADSen.(2) By steady-state fluorescence spectroscopy, the association constants betweenα-,β-, y-CD and DNSA or PAADSen were determined separately and the effects of ionic strength and polarity of solvent on association constant were studied separately. The results indicate that,α-CD can’t bind DNSA and PAADSen into its cavity,β-CD’s capacity of binding DNSA or PAADSen is stronger thanγ-CD’s; the introduction of PAA chain can reduce the binding capacity of cyclodextrins to dansyl groups grafted in PAA, this phenomenon is more obvious forβ-CD/PAADSen inclusion thanγ-CD/PAADSen inclusion; the association constant increase with the ionic strength increasing; the association constant decrease with decreasing polarity of solvent.(3) Rheological method was used to confirm the structure of networks formed by PAAp-CDen and PAADSen. The association constant between dansyl group andβ-CD group was determined by UV-Vis spectrometry method. The results show that, the viscosity of PAAP-CDen/PAADSen mixture is bigger than the single polymer. which accounts for the formation of polymer networks; the stoichiometric ratio ofβ-CDen and DSen is 1:1 because the maximum mixture viscosity occurs at this ratio; the association constant ofβ-CDen/DSen (K=27.5±3dm3·mol-1) is much smaller than that ofβ-CD/DNSA (K=103±5dm3·mol-1).

Related Dissertations

  1. Study on Rheological Properties of Rabbit Skeletal Myosin under Different Conditions,TS251.1
  2. Molecular Recognition Based on β-cyclodextrin and Chemical Modified β-cyclodextrin as Receptor,O636.12
  3. Eucommia and off , to the heart of exercise on exercise capacity and hemorheology in rats and other indicators of impact studies,G804.2
  4. New synthetic hirudin Hirulog-s anti- arterial thrombosis and anti disseminated intravascular coagulation in rats,R965
  5. Architectural membrane modification and UV coating properties,TU561.6
  6. Chitosan long tow key production technology research and development,TQ340.64
  7. Study on the Preparation of Ursolic Acid /β- Cyclodextrin Inclusion Complex by Ultrahigh Pressure,TQ461
  8. The Study on Coal Ash Fusibility and Viscosity-temperature Characteristics,TQ530
  9. Effect of Side-Chain Structure of Comb-Coplymers on Oil Flow Ability,TE621
  10. Polyester ion exchange fabrics Preparation and adsorption theory and performance,TS156
  11. Effects of TNF-α on the Transcytosis of Ldl Accross Vascular Endothelial Cells and the Underlying Mechanism,R965
  12. Recrystallized SiC slurry Rheological,TQ174.1
  13. Hydroxypropyl cellulose fiber used as preparation and Solution Properties,TQ352
  14. Core-shell polyacrylate emulsion and Application Performance Studies,TQ630.4
  15. Natural silk protein emulsion stability mechanism and interface,O647.2
  16. Geometric Pattern’s Rheology of Modern Han Folk Dress and Its Apocalypse,TS941.12
  17. The Study of the Dynamic Role of the Folk Artists in the Changes of Haicheng Stilts Yangko,J722.211
  18. Study on Preparation and Characterization of Collagen from Carp Scales,TS254.9
  19. Research on Low DE Maltodextrins from Rice Starch,TS231
  20. Process and mechanism of high strength aluminum alloy composite welding with ultrasonic agitation,TG453.9
  21. Fermentation Production Process of Novel Microbial Polysaccharide-Welan Gum,TQ929

CLC: > Mathematical sciences and chemical > Chemistry > Polymer chemistry ( polymer ) > Natural polymers ( polymer ) > Polymer polysaccharides
© 2012 www.DissertationTopic.Net  Mobile