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Objective To investigate the relationship between left ventricular diastolic function in patients with essential hypertension of left atrial volume index (LAVI) to provide a more reliable indicator for the assessment of left ventricular diastolic function in patients with essential hypertension. Method in patients with essential hypertension in 110 cases, and the healthy control group of 30 patients (group 1), underwent routine echocardiography get by mitral early diastolic left ventricular filling peak speed (E), late diastolic left ventricular filling two-chamber view of the peak velocity (A), apical four-chamber view, and left ventricular systolic left atrial volume, left atrial area (A,, A2), and measure the mitral annular midpoint to the top of the left atrial distance (L1, L2) and other parameters, calculate the E / A ratio, LAVI; the line pulse tissue Doppler imaging (PW-TDI) detection for diastolic function parameters: mitral annulus myocardial tissue diastolic early and late diastole peak speed (respectively Em, Am), systolic function parameters: systolic peak velocity (Sm) and calculated Em / Am, E / Em ratio. Hierarchical set the appropriate reference to the United States echocardiography Figure Association recommended standards, the degree of impairment of left ventricular diastolic function in patients with essential hypertension from light to heavy in turn divided into 0-3 diastolic dysfunction and diastolic dysfunction in patients group: Group 2: normal diastolic function group (0, 1 lt; E / A lt; 2, Em / Am gt; 1, E / Em ≤ 8); Group 3: early diastolic dysfunction group (a , E / A lt; 1, Em / Am (1,8 (E / Em lt; 15); Group 4: pseudonormal group (2, 1 lt; E / A lt;, Em / Am ( 1,8 (E / Em lt; 15); Group 5: the restrictive filling obstacle group (3, E / A gt; 2, Em / Am lt; 1, E / Em ≥ 15). hypertension diastolic function normal group, and diastolic dysfunction in each group LAVI and healthy control groups were compared, and LAVI and conventional ultrasound indicators, PW-TDI indicators for the assessment of left ventricular diastolic function and pseudonormal discriminant value control analysis. 1 2-5 group of hypertensive patients with diastolic dysfunction from light to heavy, Em gradually reduce the difference between the groups was statistically significant (P lt; 0.05);, E / Em ratio increased accordingly, Group 5 gt ; Group 4 gt; Group 3 gt; group 2, group differences were also statistically significant (P lt; 0.05). 2 normal group with hypertension group Em E / Em ratio was no significant difference (P gt ; 0.05). 2. 2-5 group to hypertensive patients from the healthy control group, LAVI values ??in turn increased group (18.95 ± 5.74ml/m2) lt; Group 2 (23.07 ± 6.30ml/m2) lt; Group 3 (32.05 ± 8.97ml/m2) lt; Group 4 (38.22 ± 12.28 m1/m2) lt; group 5 (50.46 ± 9.90ml/m2) difference between the groups was statistically significant (P lt; 0.05). 3. The analysis showed that: of age, left ventricular (LVEDd), left ventricular mass index (LVMI), body mass index (BMI), diastolic dysfunction grading E / Em ratio, DBP and LAVI positive correlation; Sm LAVI negative correlation (P lt; 0.05) LAVI for the strain of many factors stepwise regression analysis showed that diastolic dysfunction classification, LVMI, Sm, BMI, age is the LAVI important influencing factors, multiple linear regression equation: LAVI = 5.795X diastolic function insufficiency grading-14.89XSm 0.63XBBMI 0.092XLVMI 0.129X age 32.057 (F = 29.158, P lt; 0.05) the 5.LAVI, E / Em and E / A ratio for the diagnosis of high blood pressure in patients with left ventricular diastolic function insufficiency area under the ROC curve are 0.841,0.877,0.225; LAVI and E / Em than E / A ROC curve area was significantly increased (P lt; 0.05) area under the ROC curve of LAVI and E / Em was not statistically difference (P gt; 0.05). LAVI, E / Em used to identify hypertensive patients with left ventricular diastolic function pseudonormal under the ROC curve area is 0.878,0.855, both showed no significant differences (P gt; 0.05 ). the conclusion 1.LAVI is a more accurate indicator of the assessment of hypertensive patients with left ventricular diastolic function. 2.LAVI the greater reflect hypertensive patients with left ventricular diastolic dysfunction is more serious. 3.LAVI may be more E / Em can earlier to reflect hypertensive patients with left ventricular diastolic dysfunction. 4.Sm, BMI, LVMI and age is the LAVI meaningful impact factors.
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