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In recent years, the use of the package cooperation between the cyclodextrin and hydrophobic object used to build the macromolecular network system to obtain more and more attention. This network structure the degree of crosslinking is easy to control, not only for the association of the polymer bonding theory provides the ideal experimental models, but also widely used in the controlled release of drug release or the polymer viscosity adjustment. Firstly single sulfonylation of γ-cyclodextrin (γ-CD) and monoamine modified after the amination Y-CD with three different length alkyl (Cn, n = 12,16,18 ) amine chain grafted to the polyacrylic acid (PAA) was successfully synthesized by the y-CD-modified polyacrylic acid (y-CD-PAA) and polyacrylic acid modified by the hydrophobic alkyl chain (Cn-PAA, n = 12,16,18), and then the y-CD-PAA and Cn-PAA complex, the use of the packet between the cyclodextrin with a hydrophobic alkyl chain, cooperation with successfully prepared macromolecule self-assembled network structure, and rheological means of a systematic study of factors affecting the structure of the polymer network. The specific studies are described below: Synthesis of the y-CD-PAA is divided into the following three main steps, first, the monomer of γ-CD 6 hydroxy monocarboxylic sulfonylated modified, purified by column chromatography to give pure 6 single sulfonylation y-CD (y-CD-6-OTs), the y-CD-6-OTs reacted with ethylenediamine, prepared six single aminated y-CD (γ-CD- 6-EDA), and finally the reaction of y-CD-6-EDA with polyacrylic acid to obtain a Y-CD-PAA, and purified by dialysis and lyophilized. Cn-PAA preparation method with the same y-CD-PAA structure and purity of all products are characterized NMR, IR, and TLC analysis. Y-CD-PAA on the basis of the successful synthesis of y-CD-PAA and Cn-PAA, and Cn-PAA complex, the corresponding polymer prepared successfully verified a high self-assembled networks, and rheology the presence of a molecular network structure, the factors affecting the network structure, such as graft-y-CD and Cn of the molar ratio, polymer concentration, different hydrophobic carbon chain length, temperature of the system were studied in detail. Draw the following conclusions: the last packet cooperation between y-CD Cn mainly quantitative models of 1:2, ie a y cyclodextrin cavity can penetrate two alkyl chains; due to the hydrophobic interaction different cooperation with the package, simple system C18-PAA the viscosity and y-CD-PAA/C18-PAA complex viscosity of the system with the system of concentration of different, showing a different law; carbon chain length from 12 to 18, The viscosity of the system increases; temperature rise due to increased thermal motion of molecules, the viscosity of the system. Finally, the article also monomer γ-CD and a surfactant sodium dodecyl sulfate (SDS), the addition of the regulatory role of the complex system and the pure C18-PAA system forming a network structure, concluded: When the monomer y-CD complex system, in cooperation with monomer y-CD Cn-PAA hydrophobic carbon chain occurs preferentially package, resulting in complex with destruction of the network structure of the system, the viscosity of the system greatly reduces, to a stable value, no change; C1 8-PAA system to simply add a small amount of monomer cyclodextrin, the viscosity of the system is to show a downward trend, continue to join with the y-CD, the viscosity of the system is reduced to a minimum value began to rise; when adding a small amount to the monomer of γ-CD-containing C18-PAA system by SDS, the viscosity of the system will gradually increase, as the SDS amount increases, the viscosity reached a maximum after started to decline, so if monomer γ-CD and SDS was added to the pure C18-PAA system, the adjustment of the structure of the polymer network can be achieved, and thus play a regulatory role in the viscosity of the system of self-assembled. The innovation of this paper is that: the function of the nature of the use of γ-CD, grafted to the poly (acrylic acid), and preparation of a new class of cyclodextrin modified polymer; take advantage of the characteristics of the guest molecules in its hydrophobic inclusion build a new class of cyclodextrin polymer network structure, and give full play to the the polymer skeleton supporting role, and lay a theoretical foundation for the cyclodextrin to expand the application in areas such as controlled drug release.
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