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Tian Qi Hypoglycemic Capsules metformin in the treatment of the Qi Deficiency type 2 diabetes clinical study

Author: LiYao
Tutor: ZuoXiaoLin;WuJie
School: Beijing University of Traditional Chinese Medicine
Course: Chinese medical science
Keywords: Type 2 diabetes mellitus Metformin Clinical Research Qiyinliangxu Of Tian Qi hypoglycemic Capsule
CLC: R587.1
Type: Master's thesis
Year: 2011
Downloads: 79
Quote: 0
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Abstract


Diabetes is a common chronic disease, caused by the interaction of genetic and environmental factors that can lead to systemic multi-system damage. In recent years, as people's living standards, increasing the incidence of diabetes is increasing year by year, and its complications is a serious threat to people's lives and health. Now give more attention to diabetes prevention and treatment of diabetes research has also become one of the focus of research at home and abroad. Currently, Western medicine hypoglycemic drugs in clinical widely used, but most of them have side effects in the treatment of diabetic convenient, efficient, and worthy the clinical systematic promotion of this article discusses the modern progress of diabetes research and the motherland of traditional medicine for diabetes, divided into The literature review and clinical studies of two parts, both of which literature review and Western medicine Review TCM Summary. Western medicine review outlines the recent years, at home and abroad on the basis of diabetes and clinical research progress, · awareness of diabetes, etiology, pathogenesis, diagnosis typing and treatment. TCM Summary section explains the ancient records, Diabetes Research Progress of Chinese medicine in the Diabetes disease etiology and pathogenesis, syndrome, treatment method, and existing problems and prospect. Objective: To study days the stilbene hypoglycemic capsules Metformin treatment of type 2 diabetes Qi Deficiency Clinical efficacy. Methods: A multicenter, randomized, double-blind, placebo-controlled method, a random number to the clinical diagnosis of the the yin type 2 diabetes 80 patients were randomly divided into two groups, 40 cases in which the treatment group days For stilbene Hypoglycemic Capsules combined with metformin, the control group, 40 patients with placebo metformin. The total duration of treatment was 12 weeks, every 4 weeks for review fasting glucose, two-hour postprandial blood glucose, physical examination and TCM symptom score. After 12 weeks, the clinical symptoms in comparing the two drugs on patients before and after treatment, and fasting blood glucose (FBG) were observed before and after treatment, two-hour postprandial blood glucose (PBG), glycosylated hemoglobin (HbA1c). Total cholesterol (CHO), triglycerides ( TG), high density lipoprotein (HDL), low density lipoprotein (LDL) changes. Results: The two groups could significantly reduce the TCM total symptom score (P <0.01), but no statistically significant difference (P> 0.05), treatment group the throat Kouzao, lassitude, thirst hi drink shortness of breath, heart palpitations and other symptoms significantly improved (P lt; 0.05, P lt; 0.01). Both groups significantly reduce blood sugar levels in patients with treatment group drop blood sugar compared with the control group more significantly (P lt; 0.05); two groups could significantly reduce HbA1c levels, but no significant difference between the two groups ( P> 0.05). 3 treatment groups to improve cholesterol and low-density lipoprotein levels significantly better than the control group (P lt; 0.05), but the two groups in improving triglycerides and high-density lipoprotein was no significant difference (P> 0.05). 4 groups were no adverse reactions. Conclusion: The use of day stilbene Hypoglycemic Capsules and metformin treatment of type 2 diabetes yin efficacy, can significantly improve the clinical symptoms of Yin Deficiency type 2 diabetes patients, lower blood sugar and improve abnormal lipid metabolism. In clinical application, no days Qi Hypoglycemic Capsules-related adverse reactions occur, can be seen in its clinical application is safe, worthy of clinical use.

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CLC: > Medicine, health > Internal Medicine > Endocrine diseases and metabolic diseases > Islet disease > Diabetes
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