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Objective: Primary liver cancer (Primary Hepatic Carcinoma, PHC) occurred in the liver cells or intrahepatic bile duct tumor cells, is one of the most common malignancies in the world. Malignant cancers worldwide, primary liver cancer incidence ranks 5-6, mortality ranking 3-4 new cases per year to more than 700,000 cases, more than 600 thousand cases of deaths, high-incidence area for China and in Africa, South Asia [1-4]. According to Ministry of Health statistics the number of liver cancer incidence in China currently accounts for about 55% of the global ranking, its incidence in some of the rural population of cancer a 2 ranking in some cities, liver cancer deaths accounted for 40% of the world. Tumor-related death after lung cancer. The treatment of choice for surgical resection of HCC, the best indication of an early small HCC, the 5-year survival rate of 60-75%. However, in patients with advanced majority, of which only 15% to 25% of the possibility of surgery [6-7]. The non-surgical treatment of patients with liver cancer treatment is very important and can play to improve outcomes, improve survival and improve the quality of life of patients, the role to create the conditions for the surgery, and even be able to achieve similar surgical cure effect. Non-surgical treatment, specifically radiotherapy, hepatic artery chemoembolization, percutaneous intratumoral local treatment, biological treatment, Chinese medicine treatment, and recent applications of radiofrequency ablation and high intensity focused ultrasound therapy, laser photocoagulation therapy, each with advantage. Radiation therapy is one of the most important non-surgical treatment, but because traditional radiation therapy lead to radioactive liver injury (Radiation-induced Liver Disease, RILD), it is difficult on hepatoma the large doses radical irradiation, severely reducing radiation therapy efficacy, limiting its application in the treatment of liver cancer [8]. Three-dimensional conformal radiation therapy (Three-Dimensional Conformal Radiotherapy, 3DCRT) primary liver cancer radiation exposure to mainstream technology, can achieve better tumor control probability (Tumor Control Probability, TCP) and normal tissue complication probability (Normal Tissue Complication Probability, NTCP) [9]. Achieve precise outline of the tumor target is a the 3DCRT key. According to the provisions of the International Radiation Units and the determination of the Commission (ICRU) 50 3DCRT target, plan to determine the target volume (Planning Target Volume, PTV) was established in the clinical target volume (Clinical Target Volume, CTV), while CTV determine Established in gross tumor volume (Gross Tumor Volume, GTV). GTV is a clinical examination and imaging findings of the tumor volume. Precise GTV sketched a great influence on the success or failure of the treatment of liver tumors. Purdy research [10]: outlining the scope of the tumor target is greater than the actual tumor volume, radiation therapy be normal tissue causing unnecessary damage, but if the target is less than the actual tumor volume, easily the tumor leakage according to will result in local control rates reduce tumor recurrence. CT and MRI technology has become the primary liver cancer imaging target delineation means, but whichever outlined GTV has not been clear advantage. Study the accuracy of the method of image acquisition means the key is how to solve the imaging level corresponds exactly with pathological levels, as well as selected tumor cases, but the reported studies have failed to better solve the above problems, the research continues to explore. This experiment means the best image sketched GTV is due to primary liver cancer underwent liver transplantation cases preoperative CT, MRI scan images with postoperative specimens comparative study of the measurement of the tumor diameter for clinical basis. Methods: 2009 to 2010, nine cases of liver transplantation in cases of primary liver cancer patients before who did not receive local treatment, previous imaging studies have shown that liver cancer nodules. Line 64 slice CT line scan three enhanced scan 3.0T the superconducting MRI scan conventional plain postoperative specimens anatomical, record the location of the tumor, the number of maximum diameter, compare different imaging techniques and postoperative specimens compliance rate of the maximum diameter of the same tumor (in accordance with standard imaging and postoperative specimens tumor maximum diameter difference ≤ 5mm), the difference between the groups related group. Results: The maximum diameter of the measurement of the same tumor, CT and postoperative specimens meet the rate of 22%, the difference was statistically significant (P = 0.017), the correlation coefficient was 0.928, MRI and postoperative specimens in line with the rate of 44%, the difference was statistically significant (P = 0.010), the correlation coefficient was 0.979. Conclusion: MRI over CT measurement of primary liver size is more accurate, more suitable outline the GTV.
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