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The Antimicrobial Research of New Nano-composite Materials XCompiosed of Geklatin-GHydroxypatite-minocycline(Gel-HA-M) for Bone Rconstruction
Author: SunChuanFeng
Tutor: ZhouJian
School: Anhui Medical University,
Course: Clinical Stomatology
Keywords: Bone repair materials Gelatin Hydroxyapatite Minocycline Antibacterial
CLC: R318.08
Type: Master's thesis
Year: 2011
Downloads: 31
Quote: 0
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Abstract
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Objective To investigate the antimicrobial properties of novel nanocomposite bone repair materials gelatin - Hydroxyapatite - minocycline (Gel-HA-M), to prove its position in the field of bone repair material and enable them to be in the field of bone defects can be more widely used. With sterile saline as the release medium, the accurately weighed taken 0.2g \in vitro release experiment, and does not contain minocycline \1d, 3d, 5d, 7d, 14d, 21d, 26d, 30d time points centrifugal samplers containing drug made from pieces of paper in the achievement of sustained-release liquid culture sp proliferation Porphyromonas gingivalis (Pg) and golden aureus using disk diffusion method Porphyromonas gingivalis aeruginosa and Staphylococcus aureus in vitro antibacterial experiments, read the inhibition zone data, compared with the control group, in order to examine the \\Results \Drug-containing pieces of paper with \gradually narrowing. \goes on, the inhibition zone gradually reduced. Drug-containing paper is still 30 days and the use of composite materials made of slow-release liquid antibacterial ring in the two bacteria inhibition experiments. \Conclusions and \. \materials.
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CLC: > Medicine, health > Basic Medical > Medical science in general > Biomedical Engineering > General issues > Biomaterial
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