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The Development of Compound Shanqishen Capsules

Author: ChenLing
Tutor: JiaoHaiSheng
School: Lanzhou University
Course: Pharmacy
Keywords: Compound Shanqishen capsule Hypolipidemic preparation quality standards
CLC: R283
Type: Master's thesis
Year: 2011
Downloads: 85
Quote: 0
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Abstract


As people’s living standards improve, the incidence of hyperlipidemia increasingly high, has an impact on people’s health one of the major diseases, but also lead to cardiovascular disease risk factors. How to lower blood lipids to reduce and prevent atherosclerosis, cardiovascular diseases and development of medical research has become a hot spot. Western medicine research and treatment of this disease has made great achievements, but long-term use of medicine caused by damage to liver and kidney function, muscle damage and lipid rebound after drug withdrawal and other side effects treatment of this disease is still a the inevitable problems. Therefore, the application of traditional Chinese medicine treatment of hyperlipidemia, give full play to traditional Chinese medicine in the treatment of traditional Chinese medicine in the diagnosis and treatment of the features and advantages of fewer side effects, with good prospects for the study. Shanqishen Capsule compound is under the guidance of traditional Chinese medicine theory, it was composed of 11 herbs such as Atractylodes, Astragalus, Shouwu, Citrus,rhubarb, cassia, hawthorn, Coptis,and so on.. It takes a function of Lipid-lowering consumer silt, Ventilation and Reduction phlegm,Add the blood and make the Spleen stronger, it mainly good for hyperlipidemia within these effects. The development of this is based on the treatment by traditional Chinese medicine principles, and with Clinical application, while retaining the basis of active ingredients, committed to removing the invalid components, take use of modern technology in pharmacy, together with the supporting role of chitosan, its become the Compound Capsules.Methodological standards with the new drug research, from the following aspects were studied:1, Prescription filter:the preparation has based on the clinical efficacy of lipid-lowering small prescription of traditional Chinese medicine. With the advantages of Lipid-lowering consumer silt, Ventilation and Reduction phlegm,Add the blood and make the Spleen stronger,makes out the Compound Shanqishen Capsules 2, the preparation process design:use the modern pharmacy techniques in order to retain the active ingredients, committed to removing the invalid components, designed to meet the preparation process.3, the preferred preparation process:take the orthogonal test of the compound shanqishen capsules to optimum extraction process to determine the best extraction.4, the quality standards identified:adoption the TLC, high pressure liquid chromatography and other methods to establish its quality control standards, this method is simple, easy, accurate and reliable. Compound Shanqishen Capsules of R & D not only for the preparation of the registration approval and further promote the use of reliable scientific evidence, as well as in patients with hyperlipidemia provide a safe, reliable, good efficacy of a new preparation.

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CLC: > Medicine, health > Chinese Medicine > Of Pharmacy > Chinese medicine processing,preparation
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