Dissertation > Excellent graduate degree dissertation topics show

Carotid Artery Wall Elasticity and Carotid Atherosclerosis in Diabetes Mellitus Patients with Microalbuminuria Using Ultrasonographic Elastography and High-freguency Ultrasound

Author: GaoZuo
Tutor: ZhangYuHong
School: Dalian Medical University
Course: Medical Imaging and Nuclear Medicine
Keywords: High-frequency ultrasound Type 2 diabetes Microalbuminuria Carotid Atherosclerosis Ultrasound Elastography The flexibility of the carotid artery
CLC: R445.1
Type: Master's thesis
Year: 2011
Downloads: 7
Quote: 0
Read: Download Dissertation


PartⅠAssessment of carotid atherosclerosis in type 2 diabetes mellitus patients with microalbuminuria with high-freguency ultrasoundObjective: To evaluate carotid atherosclerosis in patients of type 2 diabetes mellitus ( T2DM ) with microalbuminuria ( MA ) by using high-freguency ultrasound.Methods: Ninty-one patients of T2DM were divided into two groups according to urinary albumin excretion rate ( UAER ): T2DM without MA (T2DM1 group, 49 ) and T2DM with MA (T2DM2 group, 42 ).The intimal-medical thickness (IMT) and the atherosclerotic plaques of carotid artery were observed in both groups with high-freguency ultrasound. Total cholesterol(TC),Triglyceride (TG),Low-density lipoprotein (LDL),High density lipoprotein (HDL),Glycosylated hemoglobin A1c(HbA1c),Uric acid (URIC),Creatinine(CREA),High-sensitivity C-reactive protein(HSCRP), Fasting plasma glucose(FPG), 2 h postprandial glycemia(2 hPG),Urinary albumin excretion rate(UAER),Body mass index(BMI) were measured.Results: The values of 2 hPG,BMI,TC,CREA,UAER,HbA1c,IMT of T2DM2 group were significantly higher than those of T2DM1 group (P < 0.05). In Pearson correlation analysis,IMT was positively and significantly associated with CREA(r =0.311; P <0.05), UAER(r =0.309; P <0.05), GHbA1c (r =0.441; P <0.05 ),course of disease(r =0.350; P <0.05). In Multivariate linear regression analysis UAER,GHbA1c and course of disease were independent predictors of IMT In two groups,the detection rate of soft plaque was higher than that of hard plague and mixed plaques (P < 0.05). Conclusions: IMT of carotid in patients of T2DM with MA was significantly increased compared with the patients of T2DM without MA.There were close correlation between IMT with UAER,HbA1c and course of disease.The high-frequency ultrasound is a convenient and effective method to evaluate carotid atherosclerosis of the patients of T2DM with MA.PartⅡAssessment of carotid artery wall elasticity in type 2 diabetes mellitus patients with microalbuminuria using ultrasonographic elastographyObjective: To evaluate carotid artery wall elasticity in type 2 diabetes mellitus (T2DM ) with microalbuminuria ( MA ) using ultrasonographic elastography.Methods: Ninty-one T2DM were divided into two groups according to urinary albumin excretion rate ( UAER ): T2DM without MA (T2DM1 group, 49 ) and T2DM with MA (T2DM2 group, 42 ) . The B/A (the ratio of elastic stiffness coefficient) of the right common carotid artery were calculated by ultrasonographic elastography. The correlation between B/A and general data were analyzed.Results: Compared with the value in the T2DM1 group, the B/A of T2DM2 group was significantly higher ( P < 0.05 ). The B/A was correlated with CREA,UAER and HbA1c (r= 0.266、P <0.05, r=0.426、P <0.05,r=0.405、P <0.05). It is the same to the first part laboratory indexes of T2DM2 group are higher than T2DM1 group.Conclusion: The carotid artery wall elasticity in T2DM with MA decreased. Ultrasonographic elastography canevaluate carotid artery wall elasticity in T2DM with MA accurately and rapidly.

Related Dissertations

  1. The Study of Cervical Lesions Imaging Characteristics and Clinical Application in Transvaginal Real-Time Elastography,R445.1
  2. The Value of Ultrasonic Elastography in the Diagnosis and Prognosis of Breast Lesions,R445.1
  3. Assess the Value of High Frequency Ultrasonography in Diagnosis of Rotator Cuff Tears and the Promise of Elastography,R445.1
  4. Competitive Adsorption of Phenolic/Ethanol onto Silica Fiber Effected by Ultrasound in RTM Process,TB332
  5. Research on Methods of Medical Ultrasound Image Denoising,TP391.41
  6. The Correlation of Ultrasound Elasticity with the Expressions of Estrogen Receptor, Progestron Receptor, C-erbB-2 in Breast Cancer,R445.1
  7. Evaluation of Left Ventricular Radial and Axis Systolic Function in Patients with Essential Hypertention Using Two-dimensional Speckle Tracking Imaging,R541.3
  8. Comparative Analysis Between Percutaneous Nephrolithotomy Under Ultrasound Guidance and Open Surgery as a Treatment in Upper Urinary Tract Stone,R699
  9. A Stduy of High Intensity Focuse Ultrasound in Loading Tumour Antigen of Dendritic Cells and Lead T Cell to Secrete Interferon-Gamma in Vitro,R392
  10. Lipid-lowering therapy reversal of coronary atherosclerosis,R541.4
  11. Comparative Study between Ultrasound and Spiral CT in Adults in the Diagnosis of Acute Abdominal Disease,R656.1
  12. Synthesis of Glycoluril under Ultrasound Irradiation,TQ226
  13. The Study of Multiple-frequency Ultrasound Assisted Leaching Curcumin from Turmeric,TQ611.3
  14. Study on the Preparation of Flavor Substances in Garlic by Multi-frequency Ultrasound Coupled with Endo-enzymatic Hydrolysis,TS264.3
  15. Study on the Determination Method of Aroma Components of Tobacco and Tobacco Essence,TS47
  16. Analysis between the Intima-Media Thickness of the Lower Peripheral Arteries, Shear Rate and Related Factors in Diabetic Patients,R445.1
  17. Three-dimentional Ultrasonography Value of Cervical Superficial Lymphadenopathy: Initial Study,R445.1
  18. Application of Intravascular Ultrasound in Assessing Borderline Coronary Artery Disease,R541.4
  19. Diagnosis and Treatment of Hepatic Artery Thrombosis after Liver Transplantation,R657.3
  20. The Effect of Low-frequency Ultrasound Combined with Nanofibrous Membrane on Bone Defect,R687.3

CLC: > Medicine, health > Clinical > Diagnostics > Diagnostic Imaging > Ultrasonic diagnosis
© 2012 www.DissertationTopic.Net  Mobile