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Part I: chronic kidney disease patients nutritional status survey and its influencing factors Objective: To understand chronic kidney disease patients hospitalized nutritional status and its influencing factors. Methods: 402 cases of hospitalized patients with CKD body mass index (BMI) and serum albumin, blood lipid components, the correlation between hemoglobin compared between patients with different BMI difference whether the clinical chemistry indicators were statistically significance. Results: 402 cases of patients with CKD BMI and HB, ALB, TP, TG, TC, LDL-C was significantly correlated (P lt; 0.05), while the HDL-C, APOA1, APOB no significant correlation (P gt; 0.05) . Odds ratio calculation: HB, ALB, TP, TC, HDL, APOB less than 1, TG, LDL, APOA1 greater than 1.291 cases of CKD patients with normal BMI group and malnourished group HB, CR, cystatin C, eGFR were No difference in overweight and obese group CR, cystatin C than malnutrition, the normal group, but HB, eGFR high obesity and overweight compared HB, eGFR is higher. When divided into two groups of malnutrition when compared with non-malnourished, CR, eGFR no difference, and malnourished patients cystatin C higher, HB low. Conclusion: HB, ALB, TP, TC, HDL, APOB chronic kidney disease protective factors, and TG, LDL, APOA1 are risk factors. HB and nutritional status which is most closely connected. In the main secondary to hypertension, diabetes, and chronic glomerulonephritis hospitalized patients, overweight and obese patients, HB, eGFR mostly higher than normal or malnourished patients, whereas serum creatinine and cystatin C were low. This may be caused by high filtration with its relevant, but it also shows that good nutrition may be better renal function. Part II: Chronic kidney disease eGFR assessment study Objective: To evaluate explore hospitalized chronic kidney disease eGFR. Methods: the simplified MDRD equation, Cockcroft-Gault formula and cystatin C estimated 292 cases of patients with CKD glomerular filtration rate (GFR), and compare the different methods to estimate the correlation between GFR. Results: 292 patients with chronic kidney disease (CKD) 1 ~ 5 on a simplified MDRD formula and the Cockcroft-Gault equation to estimate GFR was significant difference (P lt; 0.05); CKD1 period and CKD3 term abbreviated MDRD formulas and to cystatin C estimated GFR was significant difference (p lt; 0.05), CKD2 period and CKD4 ~ 5 period there was no significant difference (P gt; 0.05). Chronic kidney disease (CKD) patients by simplified MDRD formula stage 1 to 5 to Cockcroft-Gaul (tCG) formula and the calculation of GFR cystatin C were significantly different (P lt; 0.05). Conclusions: Many estimating glomerular filtration rate method, although the exact value can not be drawn, but still has its significance.
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