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Stomatitis Kang Duicheng people periodontitis patients GCF cytokine expression Intervention Research

Author: YangJian
Tutor: ChenJianLing
School: Guangzhou University of Traditional Chinese Medicine
Course: TCM features science
Keywords: Periodontitis GCF Cytokines Stomatitis oral health
CLC: R276.8
Type: Master's thesis
Year: 2009
Downloads: 33
Quote: 0
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Abstract


Objective: Periodontal disease is a common disease of human oral disease, oral health has great destructive oral two diseases. Can occur in the same age group. Modern medicine, periodontitis periodontal pathogens primarily through its products and excessive host response to periodontal tissue destruction caused. In this study, the application of modern experimental equipment and testing instruments, stomatitis Kang observed in patients with periodontitis GCF cytokine expression intervention, and explore stomatitis Kang on cellular immunity in patients with periodontitis humoral immunity and thus investigate the treatment of periodontitis Kang stomatitis mechanism of action for the clinical treatment of periodontitis using stomatitis Kang provide theoretical guidance. This study aimed to gather information on clinical cases of periodontal disease, is characterized by cases of laboratory testing project, and its clinical syndrome, as a combination of Chinese and Western medicine treatment of periodontitis explore a starting point for the development of best treatment programs, improve the clinical efficacy basis. Methods: A prospective clinical research methods, by calculating the sample size and analysis of the actual situation, to come to our hospital for observation and diagnosis of patients for first registration and follow-up, were randomly divided into treatment group and control group, the the treatment group and the control group of patients GCF IL-1, IL a 6, TNF-α, and other clinically relevant indicators detected as the base value. Control group with conventional treatment methods, namely, oral hygiene instructions, supragingival and subgingival scaling and other basic treatment. Treatment group were stomatitis treatment based on the use of oral health for two weeks of drug treatment. Two weeks after the referral is detected again observe the teeth GCF and clinical outcome measures. Collecting relevant information, the data and information databases. Through statistical analysis, to explore stomatitis oral liquid on patients with periodontitis GCF Cytokines intervention role. Results: The total effective rate 79.49% in the control group was 29.16%, the two groups had significant difference (P <0.01); 2 groups of patients in the clinical symptoms of recovery there was a significant difference (P <0.05) . Stomatitis oral liquid on patients with periodontitis GCF Cytokines role of intervention has been initially confirmed. Conclusions: 1. Further confirmed through clinical research, stomatitis oral liquid on the treatment of patients with periodontitis is a positive and effective, can significantly improve related symptoms in patients with periodontitis. 2 through clinical observation, stomatitis oral liquid on patients with periodontitis GCF intervention role of cytokines preliminary validation.

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