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Study on Safety Performance of a New Type of Solid SE-FAE

Author: DuJiaLi
Tutor: HuiJunMing
School: Nanjing University of Technology and Engineering
Course: Safety Technology and Engineering
Keywords: The solid cloud burst agent Compatibility Stability DSC Mercury manometer
CLC: TQ560.7
Type: Master's thesis
Year: 2009
Downloads: 105
Quote: 2
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Abstract


This paper focuses on a new type of solid cloud burst Pharmacy in the design and use of performance optimization problems explored Pharmacy Some important safety performance indicators , of Pharmacy in the transportation, storage, security and pharmaceutical process of using the desired effect reliability Assessment of significance. Pharmacy security features include pharmaceutical compatibility, stability and sensitivity . Is divided into two parts: the compatibility between the various components within compatibility ; is of Pharmacy to their frequent contact with the material between Foreign Minister capacitive . Within the compatibility of differential scanning calorimetry fuel in accordance with the subject of the national army , the use of the thermal decomposition process of DSC instruments measured at different heating rates for each component system , and compared with the mixed system , the instrument collected data using two kinds of thermodynamic analysis method for processing the results of the two methods are basically the same , we further verified with a mercury manometer , with reference to the subject of the national army criterion deviation system DSC measured the level of compatibility with the literature , comprehensive judgments compatibility between the components of the cloud burst agents and pharmaceutical test with a mercury manometer and regular contact with the Foreign Minister of the material capacitive In addition, through the impact sensitivity , shock sensitivity spark sensitivity and shootings sensitivity of several testing methods the combination of a comprehensive evaluation of the safety performance of the agents . After the cloud burst agents after long-term inventory , due to the change of the physical and chemical properties and environmental factors , its safety and reliability will be affected . Therefore, the study drug stability is particularly important, in this article with the vacuum stability test mercury manometer method testing the thermal stability of the medicament , and finally , the use of the thermal accelerated aging test prediction pharmaceutical the theoretical storage period at room temperature . The qualitative and quantitative research on the the cloud burst agent safety performance indicators , provide the basis for determining the optimization formulation of pharmaceutical and industrial production .

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