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Exploratory Research on Fatty Liver Disease as Predictive of Factor the Metabolic Syndrome

Author: LiPing
Tutor: FuXiaoYing
School: Nanhua University
Course: Inner science of endocrine
Keywords: Fatty Liver Disease(FLD) Metabolic Syndrome(MS) metabolic disorders
CLC: R589
Type: Master's thesis
Year: 2008
Downloads: 148
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Abstract


Objective: To observe and analyzed the distribution and relates situations of the fatty liver and glucose and lipid metabolic disorders in randomly selected population. Representation the fatty liver was earlier the Metabolic Syndrome in clinical. It could provide a clinical basis for precautions of the Metabolic Syndrome and its vascular diseases.Methods: We used cluster sampling transverse plane to investigate metabolic disorders in those samples. There were 2394 health persons in our study, who set up health records(including age, sex, height, weight, BMI, waist circumference, blood pressure, heart rate, family history, personal history, blood lipid, liver function, fasting plasma glucose, renal function, hepatitis B, B-ultrasound). 2394 subjects were assigned to simple Fatty Liver Disease group, simple Metabolic Syndrome group, complicated with Fatty Liver Disease and Metabolic Syndrome group, normal group. Fatty Liver Disease group and Metabolic Syndrome group were diagnosed by diagnostic criterion. All dates were analyzed by SPSS13.0 and cross-sectional investigation method.Results: 1. There were 2394 complete cases in our study, Mean age were 44.42±14.95 years old. 1506 cases was??e and mean age was 43.79±14.96 years old, 888 cases was female and 45.5±14.86 years old. 433 subjects are found had FLD (18.1%). 363 subjects were found MS (15.2%). 2. The peak prevalence of FLD is 31-40 years, while the MS is >60 years. 3. The waist circumference, body weight, body height, BMI, SBP, DBP, ALT, AST, TG, Tch, FPG were higher in FLD and MS than that in control group (P <0.01). The waist circumference, BMI, DBP, AST, TG, FPG had significant difference between simple FLD group and simple MS group (P>0.05).4. Tested by chi-square criterion, incidence rate of FLD was higher than dysglycemia’s in MS. 5. The waist circumference, BMI, DBP, TG, FPG, FLD are the risk factors of MS. Conclusions: 1. There are high prevalence of FLD and MS in people health. 2. FLD is one of MS’s index , and the presence of FLD might predict the development of metabolic syndrome。

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CLC: > Medicine, health > Internal Medicine > Endocrine diseases and metabolic diseases > Metabolic diseases
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