Iron deficiency anemia is one of the world, especially the developing countries, the most common nutritional deficiency. Pointed out that the World Health Organiz" />

Dissertation > Excellent graduate degree dissertation topics show

Study on Effect of Iron Supplementation to Improve Anemia Population in Shanghai

Author: WangZhengYuan
Tutor: SunJianQin
School: Fudan University
Course: Nutrition and Food Hygiene
Keywords: Iron deficiency anemia Children and Adolescents Women of childbearing age Old people Iron
CLC: R151
Type: Master's thesis
Year: 2011
Downloads: 72
Quote: 1
Read: Download Dissertation

Abstract

Iron deficiency anemia' dissertation">Iron deficiency anemia is one of the world, especially the developing countries, the most common nutritional deficiency. Pointed out that the World Health Organization in 2001 to around 40 billion to 50 billion people (representing 66 percent of the world's population to 80%) in iron deficiency states, 20 million people (accounting for more than 30% of the world's population) anemia mainly due to iron deficiency , of which 90% live in developing countries, iron deficiency anemia in particular predilection for children, women of childbearing age and the elderly. 2002 China National Nutrition and Health Survey results show that Chinese residents prevalence of anemia was 20.1%, including 15.8% of men and 23.3% for women; urban residents was 18.2%, and 20.8% in rural areas, the prevalence of anemia in the elderly increase with age upward trend. Iron deficiency anemia can make physical activity reduced ability, memory loss, low learning efficiency, decreased immunity, resulting in a low level of population health. [Objective] The study was designed by iron supplements and dietary surveys to understand the effect of dietary nutritional characteristics of iron-deficiency anemia iron supplements Shanghai children and adolescents, women of childbearing age, the elderly, and ways of maintaining this part of the crowd normal iron storage conditions total iron intake, and analysis to promote or inhibit iron absorption and utilization of dietary factors, and to understand the impact of different dietary factors of iron deficiency anemia, and provide the basis for improving the health of iron deficiency anemia in high-risk groups and to develop interventions and methods. By adjusting the diet structure, correct irrational eating behavior, increase the intake of iron, to improve the bioavailability of iron, to achieve the purpose of prevention and improvement of iron-deficiency anemia. Group of children and adolescents [method]: to recruit 75 subjects from two primary schools in Minhang District, to meet the requirements of 146 (intervention group and 71 in the control group, aged 6 to 10 years old), school units were randomly divided into intervention group and the control group. The survey included general survey, three consecutive days of 24-hour dietary survey and physical tests. 2000 Dietary Reference Intakes the standard evaluation dietary energy and nutrient intake status. The childbearing age Wanita: recruitment to meet the standards of the 74 women of childbearing age (21 to 45 years old), hemoglobin randomly divided into intervention and control groups. The survey contains a general survey, dietary frequency questionnaire and the 24-hour dietary recalls. The 2007 Dietary Guidelines for the standard evaluation dietary structure, the 2000 Dietary Reference Intakes for standard evaluation of dietary energy and nutrient intake status. Older group: the recruitment of subjects to meet the requirements of 76 (25 male, 51 female, age 60 to 79), and both the intervention group. The survey contains a general survey, dietary frequency questionnaire and the 24-hour dietary recalls. To 2010 elderly Dietary Guidelines for the standard evaluation dietary structure, the 2000 Dietary Reference Intakes for standard evaluation of dietary energy and nutrient intake status. Intervention and control groups, daily oral administration of a package of iron nutrition package (the main component of ferric pyrophosphate and ferrous fumarate containing elemental iron 8mg) and placebo, for taking six months to observe the effect. Intervention before, during, and after the hemoglobin, serum ferritin and C-reactive protein and iron deficiency anemia related indicators of inspection and investigation. [Results] children youngsters group: after intervention, the intervention group students hemoglobin level of 107.0 g / L significantly (P lt; 0.01) rose to 121.8 g / L, the control group from 107.8 g / L significantly significantly (P lt; 0.01) rose to 120.2 g / L, the difference between the groups was not statistically significant. Hemoglobin ≥ 115g / L that the number of non-anemic control group, the intervention group were 57 (81.4%) and 58 (82.3%) were significantly higher than the baseline survey (P lt; 0.01) difference between the groups was not statistically significant . Serum ferritin levels after the intervention, the intervention group significantly 16.9ug / L (P lt; 0.01) rose to 42.2g / L, the control group by 22.4ug / L, significantly (P lt; 0.01) rise of to 35.2ug / L group between the difference was not statistically significant. Intervention group, 149.7% rise significantly higher than (P lt; 0.01) 57.1% of the control group. Final serum ferritin ≥ 15ug / L that iron stores are adequate number of intervention and control groups were 69 (98.6%) and 60 (86.8%). The average intake of more than 80% of the anemia student calcium, zinc, VA less than 60% of the recommended intake, there are a lot of student energy, VB2, VC intake is less than 80% of the recommended intake. Dietary iron intake in the intervention group, the control group were 10.3mg / d and 11.5mg / d, the control group was significantly (P lt; 0.01) higher than the intervention group, 74.8% iron from plant foods. The total iron intake (dietary the iron plus supplemental iron) and hemoglobin was positively correlated (r = 0.36, P lt; 0.01), children and adolescents with a daily intake of 13.0mg iron to make hemoglobin ≥ 115g / L The two groups of student body measurements and physical indicators were significant increases in the intervention group overall rise. Total iron, VC, and meat intake iron deficiency anemia in children and adolescents with protection factors (P lt; 0.05). Childbearing age Wanita: After six months of intervention, the intervention group hemoglobin levels from 104.9 g / L was significantly (P lt; 0.01) up to 116.8g / L, control group from 104.4 g / L becomes 104.5 g / L, the intervention group The hemoglobin significant (P lt; 0.01) higher than that of the control group. To the end of the intervention group hemoglobin ≥ 120g / L and 15 (44.1%), significantly higher than 5 (P lt; 0.01) control group (14.3%), the intervention group hemoglobin ≥ 120g / L possibility of control group 4.7 times (95% CI: 1.5 ~ 15.2). In addition, the intervention group HCT, MCV, MCH and MCHC anemia related indicators showed an upward trend (P lt; 0.05), the final stage were significantly higher than those in the control group (P lt; 0.01,0.01,0.01,0.01,0.05 for). After six months, the intervention group was significantly (P lt; 0.01) rose to 14.6ug / L, the control group by 4.4ug / L of becomes 6.2ug / L serum ferritin levels by 4.7ug / L, late intervention group serum iron The protein levels were significantly (P lt; 0.01) higher than that of the control group. Intervention group, serum ferritin ≥ 15ug / L 11 (35.5%) was significantly (P lt; 0.01) higher than that in the control group (12.1%) people. The possibility of intervention group, serum ferritin ≥ 15ug / L is 4.0 times that of the control group (95% CI: 1.1 to 14.3). Anemia in women of childbearing age energy, calcium, iron, zinc, VA, VB,: VC's average intake volume is less than 80% of the recommended intake or Adequate Intake. The average dietary iron intake of 14.0mg / d, a significant (P lt; 0.05) lower than the recommended intake of dietary iron from plant foods. Total iron intake (dietary iron plus iron supplement) and hemoglobin values ??were positively correlated (r = 0.57, P lt; 0.01), women of childbearing age, the daily intake of 23.2mg iron can make of Hb ≥ 120g / L. Total iron intake and more protective factors of iron deficiency anemia, and dietary fiber intake of more than menstrual flow risk factors (P lt; 0.05). Elderly group: older women better compliance than men. After intervention, the the older men hemoglobin level from 115.5 g / L becomes 114.4 g / L, female hemoglobin value of 111.4 g / L increased to 114.4 g / L, overall, rose by 112.5g / L to 114.4 g / L. The hemoglobin standard in the final number of 20 (32.3%), of which 16 were females (34.8%). Interim, final serum ferritin levels were as 55.1ug / L, 40.1ug / L were significantly (P lt; 0.01) higher than the baseline when 9.1ug / L. To the end of the intervention, 50 (80.1%) serum ferritin standards, including 40 females (87.0%) and 10 males (62.5%). The possibility of the female serum ferritin standard male 4.0-fold (95% CI: 1.1 to 15.1). The average intake of elderly fruit and dairy only 67.3g and 100.3g, and serious lower than the recommended intake. The elderly average intake of protein, zinc and VC volume of less than 80% of the recommended intake of calcium, VA, VB2 less than the recommended 60%. 74.4% iron from plant foods. Elderly total iron intake (dietary iron plus iron supplementation) were positively correlated with hemoglobin (r = 0.70, P lt; 0.01), older men daily intake of 26.2mg iron can hemoglobin ≥ 130g / L, older women daily intake of 22.3mg iron allows hemoglobin ≥ 120g / L. Total iron, VC and meat intake more than and a high BMI is the elderly protective factors of iron deficiency anemia, like to drink coffee and egg intake more risk factors (P lt; 0.05). [Conclusion] children and adolescents: a continuous period of six months a daily supplement 8mg iron can improve children and adolescents with iron deficiency anemia. Children and adolescents ≥ 13.0mg daily iron intake can prevent iron-deficiency anemia. Women of childbearing age: six consecutive months a daily supplement 8mg iron can effectively improve the iron deficiency anemia in women of childbearing age. Daily iron intake, women of childbearing age ≥ 23.2mg prevention and treatment of iron deficiency anemia. Elderly people: six consecutive months a daily supplement 8mg iron can effectively improve the iron deficiency anemia in the elderly. Older men daily iron intake ≥ 25.0mg and older women ≥ 22.6mg per day can prevent iron-deficiency anemia.

Related Dissertations

CLC: > Medicine, health > Preventive Medicine,Health > Nutrition, hygiene,food hygiene > Nutrition
© 2012 www.DissertationTopic.Net Mobile