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The purpose of: 1 master gastric Hp the distribution of characteristics in the crowd, epidemiological data related prevention and treatment of diseases of the stomach Hp; master oral Hp plaque, gargle and gastric mucosa in the distribution, and further explore periodontitis patients with oral Hp distribution characteristics, to establish the correlation of periodontitis, oral Hp and stomach Hp, provide the basis for the prevention and treatment of oral Hp-related diseases. Methods: 1. Gastric Hp infection assay using 14C-urea breath from August 2009 to December to Shanghai Songjiang Area Examination Center participate in the examination of 7855 examinees, SPSS 13.0 software for statistical analysis. 2 Select the period August 2009 to December physical examination were 102 cases of upper abdominal discomfort in Songjiang District Central Hospital has screened periodontitis are suffering from a study of 102 cases of periodontitis group (42 cases) and periodontal healthy control group (31 cases). PCR assay plaque gargle Hp by 14C-urea breath test method, Gram staining and PCR the joint detection stomach Hp group between groups were oral Hp and stomach within Hp positive rate comparison. Results: 7855 medical examination center survey gastric Hp infection, 3958 of stomach infection Hp, the total positive rate was 50.39%; 20-30 age group, the stomach 673 Hp positive, the positive rate was 45.47% ; 31-40 age group, gastric Hp positive for 967, the positive rate was 48.21%; 41-50 age group gastric Hp positive for 1268, the positive rate was 57.25%; 51-60 age group, gastric Hp positive for 1031, the positive rate was 49.07%; gt; 60-year-old group, stomach 19 Hp positive, the positive rate was 35.85%. Gastric Hp positive rate of all age groups, the difference was statistically significant (P = 0.000). Male, female stomach Hp positive rate was no difference (P = 0.068). 2.102 cases of subjects, oral 64 Hp positive oral Hp total positive rate was 62.75%. 3.102 cases of subjects, gastric Hp positive 72, the total positive rate was 70.59%. 52 4.64 Oral Hp positive gastric Hp positive, the positive rate was 81.25%, 20 38 oral the Hp negative, stomach Hp positive, the positive rate was 52.63%, both significant difference in the positive rate oral Hp and gastric Hp positive correlation (P = 0.002, OR = 3.90). 5.42 cases of periodontitis, oral Hp positive and 34, accounting for 80.95% of the patients with periodontitis group, oral Hp positive and 15 of the 31 patients with periodontal health, accounting for 48.39% of the patients with periodontal health group, both positive The rate difference was statistically significant, and oral Hp with periodontitis positive correlation (P = 0.003, OR = 4.53). 6.42 cases of periodontitis, gastric Hp positive and 37, accounting for 88.10% of the patients with periodontitis group, 31 patients with periodontal health, gastric Hp positive and 13, accounting for 41.94% of the patients with periodontal health group, both positive The rate difference was statistically significant, and of gastric Hp and periodontitis positive correlation (P = 0.000, OR = 10.25). 7.42 cases of periodontitis, 34 patients with oral Hp positive gastric Hp positive 32 cases, accounting for 94.12% of the oral Hp positive; eight cases of oral Hp negative, six cases of gastric Hp positive, accounting for oral Hp-negative by 62.50%, both positive rate difference was statistically significant, the periodontitis those oral Hp positive gastric Hp positive for a positive association. (P = 0.013, OR = 9.60). Conclusion: 1, the Songjiang old town stomach of Hp total positive rate was 50.39%, the highest Hp positive rate of 41-50 years, 57.25%. Hp positive rate of all age groups stomach difference was statistically significant (P = 0.000), male, female stomach Hp positive rate differences. Hp exists. Oral, oral Hp positive gastric Hp positive. Positive association (OR = 3.90), oral Hp positive than negative stomach Hp infection rate (P = 0.002). The 3 oral Hp periodontitis positive association (OR = 4.53), oral periodontitis patients with periodontal health Hp positive rate (P = 0.003). 4 stomach Hp with periodontitis positive association (OR = 10.25), periodontitis by intragastric Hp detection rate in periodontally healthy subjects (P = 0.000). 5 periodontitis in oral of Hp positive its stomach Hp positive for a positive association (OR = 9.60), gastric Hp infection by oral Hp positive rate (P = 0.013).
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