Dissertation > Excellent graduate degree dissertation topics show

Association of QT Dispersion and Tei Index in Hypertensive Patients with Left Ventricular Hypertrophy

Author: HuiYuanZuo
Tutor: XiaDaoZi
School: Dalian Medical University
Course: Medical Imaging and Nuclear Medicine
Keywords: hypertension left ventricular hypertrophy QT dispersion Tei index
CLC: R541.3
Type: Master's thesis
Year: 2010
Downloads: 71
Quote: 1
Read: Download Dissertation

Abstract


Objective:Hypertension is a disease characterized by end-organ complications, leading to left ventricular hypertrophy (LVH) in about one third of hypertensive patients. LVH increases the risk of cardiovascular morbidity and mortality, and is an independent risk factor for sudden death, coronary heart disease, congestive heart failure. QT dispersion (QTd) is a marker of inhomogenenous ventricular repolarization and electrical instability, and therefore has the potential to predict ventricular arrhythmias and sudden death. Tei index measured with Doppler echocardiography reflects left ventricular systolic and diastolic function. The index is simple,noninvasive, easy to estimate and reproducible. The aim of this study was to investigate the correlation between QT dispersion and Tei Index in hypertensive patients.Methods:127 patients wiith hypertension (62 with LVH and 65 without LVH) and 76 normal control subjects were studied. The following parameters, including left atrial diameter (LAD), end-diastolic left ventricle diameter (LVD), interventricular septum thickness (IVST), left ventricle posterior wall diastolic thickness (LVPW) and left ventricular ejection fraction (LVEF%), were measured with echocardiogram. We measured peak E and A transmitral Doppler velocities, and estimated E/A ratio.Tei index and its components, isovolumetric relaxation time (IRT), isovolumetric contraction time (ICT), and the ejection time (ET), were measured from left ventricular outflow and mitral inflow Doppler velocity profiles. The dispersion of QT intervals was defined as the difference between the maximum and minimum of QT interval which could be measured in any of the electrocardiogram leads and was represented as QTd. Results:1.Compared with the control, both the LVH group and the non-LVH group had an significant increase in LAD、LVWI、Tei index and QTd.2. LAD、IVST、LVPWT、LVMI and E/A were significantly higher in the LVH group compared to the non-LVH group.3.Tei index and QTd were significantly increased in the LVH group compared to the non-LVH group.4. Tei index was positively correlated with ICT、IRT、LVMI、IVST、LVPWT and QTd, and negatively correlated with LVDd、E/A and EF in the LVH group.5.QTd was positively correlated with LVMI、Tei index、IVST、LVPW、LVDd、E/A, and negatively correlated with EF in the LVH group.Conclusions:Hypertension may lead to the Tei index and the QTd increasing and the LVEF decreasing. QTd was positively correlated with the left ventricular hypertrophy and Tei index, and was negatively correlated with the LVEF. The LVEF、Tei index and QTd are simple and reproducible methods for the assessment of left ventricular dysfunction in hypertensive patients with LVH. Therefore we should measure above-mentioned parameters as early as possible to prevent the development of arrhythmias and to guide the use of hypotensive drug.

Related Dissertations

  1. To Observe the Clinnical Effect of Bu Shen Huo Xue Haustus Treating Kidney-Asthenia and Blood Stasis of Old Patients with Hypertension,R259
  2. Isolated systolic hypertension in patients with cardiac ultrasound characteristics of traditional Chinese medicine dialectical correlation exploration,R544.1
  3. Integrative treatment of elderly patients with hypertension TCM syndromes and quality of life,R544.1
  4. Research on Relationship between Different TCM Dialectical Type and Associate with Sex Hormones and Risk Factors of Cardiovascular Disease in Perimenopausal Women of Hypertension,R259
  5. Association between Microalbuminuria and Cardiovascular Events in the Patients with Primary Hypertension,R544.1
  6. Clinical Study on Relationship Among Syndrome Differentiation Clssified in Tcm,ambulatory Blood Pressure Monitoring and Transcranial Doppler in Essential Hypertension,R259
  7. Study on Knowledge, Attitude, and Behavior to Calcium Nutrition Among Patients with Hypertension in a Community,R473.2
  8. Evaluation of Left Ventricular Radial and Axis Systolic Function in Patients with Essential Hypertention Using Two-dimensional Speckle Tracking Imaging,R541.3
  9. Heterogeneity and Meta Analysis of the Essential Hypertension Risk Assessments,R544.1
  10. Evaluation of Right Ventricular Function in Patients with Hypertension Without Left Ventricular Remodeling by Tei Index, Two-dimensional Strain and Quantitative Tissue Velocity Imaging,R541.3
  11. Effects of High-salt Dieet on Blood Pressure and the Remodeling of Carotid Arteries and the Intervention of Telmisartan in Wistar Rats,R544.1
  12. Serum Levels of Insulin Like Growth Factor-1 and Cardiovascular Remodeling in Patients with Hypertension,R544.1
  13. The Effects of Telmisartan on Essential Hypertension with Paroxysmal Atrial Fibrillation,R541.75
  14. Effects of Telmisartan on hs-CRP and HMW-adiponectinin Patients with Essential Hypertension,R544.1
  15. Study of Right Ventricular Contraction Synchrony and Function in Patients with Pulmonary Arterial Hypertension,R543.2
  16. The Research of the Risk Factors for Vascular Cognitive Impairment in the Inpatients with Hypertension between Different Stages,R544.1
  17. Effect of Different Emotion Regulation Modes on Activities of Autonomic Nervous System of Essential Hypertensive Patients with Type A Personality under Emotion Stimulis,R544.1
  18. Association of Genetic Variation of UTS2 Gene with Type2 Diabetes Mellitus and Hypertension,R587.1
  19. Integrative treatment of acute hypertensive cerebral hemorrhage,R743.3
  20. 2D speckle tracking imaging technology assessment in patients with essential hypertension left ventricular systolic function value,R541.3
  21. Explore elastosonography carotid artery in patients with essential hypertension and flexibility in the application of radial artery,R544.1

CLC: > Medicine, health > Internal Medicine > Heart, blood vessels ( circulatory ) disease > Heart disease > Hypertensive heart disease
© 2012 www.DissertationTopic.Net  Mobile