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Analysis of 18F-FDG PET/CT Imaging of Patients with Painful Schmorl’s Nodes

Author: WangZhengMing
Tutor: ChenXianYing
School: Dalian Medical University
Course: Nuclear Medicine
Keywords: Intervertebral disk displacement Positron emission tomography Tomography X-ray computed
CLC: R816.8
Type: Master's thesis
Year: 2010
Downloads: 47
Quote: 1
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Abstract


Objective: To analyze the painful Xu Mohs nodules 18F-FDG PET / CT imaging characteristics, to improve the accuracy of diagnosis and differential diagnosis to reduce invasive diagnostic methods and the application of unnecessary treatment, thereby reducing patients medical risk, reduce the cost of diagnosis and treatment of patients. : Painful Xu Mohs nodules in 10 cases, vertebral metastases 18 cases. Observe the respective PET / CT images from the CT image form, the form of 18F-FDG metabolism and between the position of corresponding relations were observed, summarizes the distribution characteristics of painful Xu Mohs nodules in the spine, CT image morphological characteristics, the morphological characteristics of 18F-FDG metabolism between corresponding to the position of the law of the relationship. ROI method measuring pain Xu Mohs nodules and for vertebral metastases lesion SUVmax t-test of the statistical methods and the use of pain Xu Mohs nodules and vertebral metastases SUVmax to determine between There is no statistically significant difference. Results: 10 patients with painful Xu Mohs nodules including 8 patients with single lesions, two cases of multiple lesions, lesions were located in the vertebral the upper endplate or lower position endplate, thoracic lesions were located in the upper end plate 1/3 department, lumbar located next bit of the vertebral end plate, accounting for 60% (6/10), 4 lesions were located in the top 1/3 of the vertebral end plate 3 in the vertebral end plates in 1/3, 3 in the endplate after 1/3. Thoracic vertebral metastases multiple, and the main lesion or lesions are located in the cancellous bone of the vertebral body. Painful Xu Mohs nodules CT morphology Although no Mohs Xu nodules typical performance, but could be summarized in four things in common: First, the vertebrae of the upper or the lower position endplate limitations defect, even if it is not obvious, but in sagittal or coronal CT reformatted images are still visible; endplate defect low-density lesions in the bone, mostly nodular, dual Chengbian mound; vertebral low-density nodules connected to the defect through the endplate and adjacent intervertebral disc; Fourth incomplete or outer edge of the fuzzy hardening with low density nodules and vertebral body contact region. Also found that painful Xu Mohs nodules near 13 within the intervertebral space 9 narrowing, accounting for 69.2%, and there is an adjacent intervertebral space See the density of the gas samples. 18F-FDG high metabolic stove nodular or banded. 18F-FDG the high metabolic District confined to the nodules and nodules (/ or) around the hardened zone. Vertebral metastases lesion site was bone destruction, bone sclerosis, or both co-exist, can be accumulated endplate, but the main lesion or lesions are still in the vertebral cancellous bone, do not have or do not have pain Xu Mohs four characteristics nodules on CT images. Painful Xu Mohs nodules and vertebral metastases compared SUVmax between the two was not statistically significant (t = 1.563 p GT; 0.05) Conclusion: pain Xu Mohs nodules in clinical and vertebral metastases phase identification. Painful Xu Mohs nodules of 18F-FDG PET / CT morphological characteristics, with vertebral metastases with identification, and 18F-FDG SUVmax painful Xu Mohs nodules and vertebral metastases identification no value . In addition, the follow-up observation for pain Xu Mohs nodules and differential diagnosis of vertebral metastases can also help.

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