Dissertation > Excellent graduate degree dissertation topics show

Effects of Naloxone on L-type Calcium Channels in Isolated Cardiomyocytes of SD Rat

Author: ZhangZuo
Tutor: WenQingPing
School: Dalian Medical University
Course: Anesthesiology
Keywords: Sevoflurane Propofol Hypotension Functional endoscopic sinus surgery
CLC: R614
Type: Master's thesis
Year: 2011
Downloads: 10
Quote: 0
Read: Download Dissertation

Abstract


objective: Observation of functional endoscopic sinus surgery with sevoflurane and propofol effectiveness and safety of controlled hypotension.Methods:40 cases of ASAⅡ-III grade elective functional endoscopic sinus surgery patients, randomly divided into two groups（n=20）. Group A is controlled hypotension group, Group B is non-controlled blood pressure group. Group A at the beginning of the operation to maintain mean arterial pressure （MAP） 70 mmHg for hypotension, to the end of surgery; Group A and B with anesthetic drugs, but B group the line controlled hypotension. According to Fromme surgical field quality score, recorded by the antihypertensive drugs did not know the same surgeon in all patients before anesthesia in surgery （T1）、immediately before surgery（T2）、surgery began 30 min（T3）、the end of surgery（T4）、10 min after the end of surgery（T5） evaluation of the surgical field quality,intraoperative continuous monitoring MAP、HR、ECG and SpO2 ,record operation time, intraoperative ECG changes after surgery blood gas analysis taken 30min.Results:Group A of T3 and T2 when MAP decreased significantly when compared（P<0.01）and returned at T2. Group A of T3, MAP also decreased compared with the Group B was significantly（P<0.01）; The two groups at each time point was no significant difference between HR（P<0.01）;Group A of blood loss and operative time was significantly less than the Group B（P<0.01）;no arrhythmia in both groups and myocardial ischemia, postoperative and preoperative electrocardiogram showed no significant change; two groups after 30min of arterial blood gas analysis were within normal limits.Conclusion: Functional endoscopic sinus surgery with sevoflurane and propofol induced hypotension can reduce bleeding and improve surgical conditions of the operative field to minimize the operative time, no obvious side effects and complications. Sevoflurane reduced the mean arterial pressure 65mmHg - 70 mmHg,can reduce the nasal mucosa microcirculation,compared to other commonly used vasodilator effect of antihypertensive drugs better, for endoscopic sinus surgery is safe, effective and feasible, more conducive to combined heart, liver, kidney and other diseases in patients with endoscopic treatment.

Related Dissertations

  1. Half-effective Target Plasma Concentration of Remifentanil Tci for Intubation during Inhalational Induction with 1.3MAC Sevoflurane,R614
  2. The Effect of Different Target Plasma Concentration on the Sevoflurane End-tidal Concentration and the Intubation Response of Old Patients with General Anesthesia Induction,R614
  3. Comparison of Sevoflurane and Propofol in Patients Undergoing Aneurysm Clamping Operations,R614
  4. Application of Sevoflurane Anesthesia in the Cardiopulmonary Bypass,R614
  5. Effects of Sevoflurane and Propofol on Heart Rate Variability During Induction of Anesthesia in Elderly Patients with Coronary Artery Disease,R614
  6. Influences of Inhalant Anesthetics on Neuromuscular Blockade Produced by Cisatracurium in the Elderly Patients,R614
  7. Sevoflurane craftsmanship and quality of research,R971.2
  8. Analysis of Two Related Factors Affecting Subjective Efficacy in Patients with Chronic Sinusitis Postoperatively,R765
  9. Sevoflurane and propofol respectively for induction of general anesthesia effect and incidence of adverse events in the meta-analysis,R614
  10. Clinical Research on Induction with Inhalation Sevoflurane in Elderly Patients,R614.2
  11. The Effect of Magnetic Field on Serum Free Radicle in Patient Undergoing Operation for Pituitary Tumor,R614
  12. Different drugs combined with epidural anesthesia on the stress of surgery,R614
  13. The Study of Remifentanil in Children Anesthesia,R726.1
  14. Application of Sevoflurane Combined with Remifentanil and Changes of BIS and AAI During General Anesthesia Induction in the Elderly,R614
  15. The Effects of Volatile Anesthetics and Neuromuscular Blockade on Transcranial Electrical Motor Evoked Potentials,R614
  16. Effect of Sevoflurane with Propofol on Stress Response during One Lung-ventilation,R614
  17. The Study of Low Flow Sevoflurane Target-controlled Inhalational Anesthesia,R614
  18. Generation Mechanism of Neurotoxic Effect of Inhaled Anesthetics and the Impact of Its Preconditioning to Cerebral Ischemia Injury of Type 1 Diabetic Rats,R96
  19. A Long-term Neuroprotective Effect of Sevoflurane Postconditioning on Traumatic Brain Injury in Rats and the Role of PI3K/Akt Pathway,R614
  20. Effects of Sevoflurane on the Neuromuscular Block Induced by Non-depolarizing Relaxants in Female or Male Patients,R614
  21. Effects of Dexmedetomidine on the Stress Reaction During Induction and Minimum Alveolar Concentration (MAC) of Sevoflurane in Adults,R614

CLC: > Medicine, health > Surgery > Surgical operation > Anesthesiology
© 2012 www.DissertationTopic.Net  Mobile