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Study on the Relation of Chronic Periodontitis and Coronary Heart Disease with Porphyromonas Gingivalis

Author: LiuJia
Tutor: ZhongLiangJun
School: Xinjiang Medical University
Course: Clinical Stomatology
Keywords: Porphyromonas gingivalis Aeromonas Polymerase chain reaction ( PCR ) Gene sequencing Coronary heart disease Chronic periodontitis
CLC: R541.4
Type: Master's thesis
Year: 2008
Downloads: 94
Quote: 0
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Abstract


The purpose of using PCR and gene sequencing in the detection of patients with coronary atherosclerotic heart disease associated with chronic periodontitis periodontal pocket periodontal pathogen Porphyromonas gingivalis Aeromonas and coronary atherosclerotic plaque the Porphyromonas gingivalis morpholine Aeromonas homology to explore the development of chronic periodontitis and coronary heart disease . Methods 36 cases of patients suffering from coronary atherosclerotic heart disease associated with chronic periodontitis , subgingival plaque samples and coronary atherosclerotic plaque samples were collected , extracted bacterial DNA , PCR samples tested Pg 16SrDNA gene , the amplification products were the determination of the gene sequence . Pg in subgingival plaque and coronary atherosclerotic plaque detection rates were 52.78% , 47.22% . By chi-square test , no significant difference in the detection rate of both , P> 0.05. Gene sequencing the Pg 16SrDNA in the subgingival plaque gene with coronary atherosclerotic plaque the Pg 16SrDNA gene has a high degree of homology . Conclusion periodontal pathogens is closely related with the development of coronary heart disease , chronic periodontitis is one of the risk factors for coronary heart disease , and provides a basis for the prevention and treatment of coronary heart disease and chronic periodontitis .

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CLC: > Medicine, health > Internal Medicine > Heart, blood vessels ( circulatory ) disease > Heart disease > Coronary arteries ( atherosclerosis ),heart disease (CHD)
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