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With the increasing development and improvement of supramolecular chemistry, pseudorotaxane and rotaxane crown ether-based, has drawn increasing attention. The paper first introduces the overview of supramolecular chemistry and molecular recognition, the concept of self-assembly, non-bonding interaction, followed by, respectively, the crown ether and secondary ammonium cation, 1,2 - bis (pyridine salt) oxide and its derivatives , paraquat and its derivatives assembled pseudorotaxane and rotaxane research progress, and several molecular machine based on a similar binding mode described. On this basis, the synthesis of several objects, with crown ether dibenzo-24 - crown-8 assembling quasi-rotaxane, using a variety of analytical tools to study the molecular recognition behavior of the single crystal and crystal The structure was analyzed. The specific contents are as follows: 1 Synthesis of the three kinds of objects 1,2 - bis (4 - propionylamino pyridine salt) ethane, 1,2 - bis (4 - benzoylamino pyridine salt) ethane, 1,2 - bis (4 - (4 - pyridyl-carboxamido) pyridine salt) ethane, and were assembled with DB24C8 prevail rotaxane. NMR Study three pseudorotaxane solution behavior, and find association constants of [1,2 - bis (4 - benzamido pyridine Salt) ethane (?) DB24C8]; X-ray diffraction studies another two quasi rotaxane crystal structure and [1,2 - bis (4 - (4 - pyridyl-carboxamido) pyridine salt) ethane (?) DB24C8] assembly behavior. Synthesized 4,4 '- bipyridine single proton / double proton Triflate, and assembled with DB24C8 prevail rotaxane. With NMR, ESI-MS, UV-Job Method two pseudorotaxane binding mode, gaseous behavior and host-guest inclusion complexes in the stoichiometric ratio; the two Pseudorotaxane association constant by NMR law and UV titration. X-ray diffraction study of 4,4 '- bipyridine single proton trifluoro-methanesulfonate pseudorotaxane with DB24C8 assembled solid-state crystal structure and self-assembly behavior. 3. Designed a number of secondary ammonium salt; study the establishment of an ammonium salt precursor synthetic route. Were used amino protecting benzyl amine methyl-benzenesulfonyl chloride, and o-nitrobenzenesulfonyl chloride, the resultant product N-benzyl-p-toluenesulfonamide and N-benzyl-o-nitrobenzenesulfonamide, respectively, with 2 -, 3 - and 4 - (chloromethyl) pyridine, the six N-alkylated product. Deprotected under different conditions of these six compounds, not been successful. Synthesis of N, N-di-benzyl ammonium bromide salt with similar success.
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