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An Investigation on the Status of Hepatitis B among Normal Population in Chaohu City

Author: GeFuYang
Tutor: YeDongQing
School: Anhui Medical University,
Course: Epidemiology and Biostatistics,
Keywords: Viral hepatitis B Epidemiological studies of serum B virus Healthy people Viral Vaccines
CLC: R181.3
Type: Master's thesis
Year: 2008
Downloads: 68
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Abstract


Study a natural population of hepatitis B infection, Chaohu City Survey Objective Chaohu natural populations of hepatitis B virus infection and spread in the population a major risk factor for improving the crowd prevention awareness, provide a basis for reducing hepatitis B virus infection. Methods for the study of Chaohu scene to the urban / rural stratification, urban residents in residential units, rural residents administrative village as a unit cluster sampling method to select municipal district 2, 4 administrative villages in rural areas. The family unit, their general demographic characteristics, medical history, family history, history of close contact such as questionnaires. Collection 3ml venous blood by ELISA hepatitis five indicators. Survey data using SPSS 13.0 software for statistical analysis. Results 1,957 blood samples in, HBsAg positive 183 cases (9.35%), HBsAb positive 878 cases (44.86%); HBsAg in gender, urban / rural distribution of the difference was not statistically significant; HBsAb in gender, urban / rural differences in the distribution of also not statistically significant. In the urban population, HBsAg in different age groups, different occupational distribution showed no significant difference (P all gt; 0.05), the degree of distribution of cultural difference was statistically significant (χ2 = 10.01, P lt; 0.05). In the rural population, HBsAg in different age groups, different occupational distribution differences were statistically significant (P all lt; 0.05), the degree of distribution of cultural difference was not statistically significant (P gt; 0.05). Univariate analysis showed that, HBsAg positive risk factor for the family, someone get hepatitis B (OR = 3.42, P lt; 0.01), using non-disposable syringes (OR = 1.42, P lt; 0.01), sharing razors (OR = 1.92, P lt; 0.05), extraction (OR = 2.14, P lt; 0.01), playing ears (OR = 1.36, P lt; 0.01), hospitalization (OR = 1.75, P lt; 0.05), tattoos (OR = 3.32 , P lt; 0.05), not hepatitis B vaccination (OR = 1.52, P lt; 0.05). Multivariate analysis results suggest that sharing razors (OR = 1.73, P lt; 0.05), family, someone get hepatitis B (OR = 3.49, P lt; 0.01), tattoos (OR = 3.71, P lt; 0.05), not hepatitis B vaccination (OR = 1.86, P lt; 0.01) is HBsAg positive risk factors. Conclusion Chaohu HBsAg positive rate, HBsAb antibody levels are higher. HBsAg positive risk factors 4, respectively, sharing razors, family, someone get hepatitis B, tattoos, not hepatitis B vaccine, which tattoo greatest impact on HBsAg positive (OR = 3.71). For HBsAg positive rate should be a risk factor for measures to reduce HBV infection; urban and rural distribution inconsistent, residents should increase publicity and education efforts immunization. Chaohu City of two natural populations of hepatitis B vaccination rate related knowledge and purpose of the investigation to understand the natural populations of hepatitis B Chaohu prevention knowledge to grasp the situation and the situation of hepatitis B vaccine; understand the impact of hepatitis B vaccination risk factors for improving the prevention population awareness, provide a basis for reducing hepatitis B virus infection. Methods for the study of Chaohu scene to the urban / rural stratification, urban residents in residential units, rural residents administrative village as a unit cluster sampling method to select municipal district 2, 4 administrative villages in rural areas. The family unit, their general demographic characteristics, medical history, family history, history of close contact such as questionnaires, Chaohu City, rural, urban residents a total of 1565 people. Collection 3ml venous blood by ELISA hepatitis five indicators. Survey data using SPSS 13.0 software for statistical analysis. The results of this survey 1565 people, hepatitis B vaccination rate was 12.08%, which fully immunized 139 people, full coverage was 8.88%, had strengthened hepatitis B vaccination is only 16 people, accounting for 1.02% of those surveyed; hepatitis B vaccination rate in age, sex, urban and rural, education and per capita monthly income distribution differences were statistically significant; throughout the vaccination rate in terms of gender difference was not statistically significant, in the age group, urban and rural, cultural level and on the distribution of per capita monthly income statistically significant. Univariate analysis showed that the rate of hepatitis B vaccination risk factors were age (OR = 0.42, P lt; 0.01), protective factors were gender (OR = 1.48, P lt; 0.05), educational level (OR = 2.92, P lt; 0.01), rural-urban distribution (OR = 1.95, P lt; 0.01) and per capita income (OR = 1.43, P lt; 0.01). Multivariate analysis results suggest that hepatitis B vaccination rate of favorable factors for urban residents (OR = 1.53, P lt; 0.05), high education level (OR = 1.77, P lt; 0.01); advanced age is the rate of hepatitis B vaccine adverse impact factor (OR = 0.49, P lt; 0.01). Conclusion Chaohu hepatitis B vaccination in urban and rural distribution inconsistent, immunization should increase publicity and education work; strengthen people's knowledge of hepatitis B-related publicity may help improve residents hepatitis B vaccination rate levels, improve awareness of hepatitis B attitude.

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