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A New Design of Software for Patch-Clamp System

Author: ZouQiao
Tutor: ZuoAnLian
School: Huazhong University of Science and Technology
Course: Biomedical Engineering
Keywords: Patch-clamp Reusable object-oriented Unified Modeling Language Class modeling
CLC: TP311.52
Type: Master's thesis
Year: 2007
Downloads: 38
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Abstract


Patch-clamp technique has become an important means of cell electrophysiological studies , now widely used in the field of study of the mechanism of cell membrane ion channel currents and cell secretion need to be informed . Based the UDA - patch clamp data acquisition system software PClamp4.0 , basic to meet the requirements of the laboratory personnel , however, the software complex structure , memory consumption is large , can not meet the needs of long experiments , unable to respond to large volumes of data operation , and not conducive to the maintenance and transplantation . In order to solve the above problems , the design of this project a new version of the patch clamp system software . In this paper, unified modeling language, the use of object-oriented analysis method on the target system analysis and class modeling . The design process of the software system uses a modular design of reusable object-oriented method . These modules include sealing test module , module of voltage-gated and ligand-gated module , the hardware interface module . The modular design can greatly reduce the complexity of the program , is conducive to reading , test and modify . This software is a Windows-based MFC application , the realization of the process , the use of multi-threaded event synchronization and memory sharing technology , the new version of the patch clamp system software with less memory consumption , fast response, easy to maintain, easy to transplant characteristics . The same time, human-computer interaction interface design, offers a relaxed , happy, feel-good operating environment for laboratory personnel . The software through the use of laboratory personnel , have been satisfied with the experimental data , the results show that the application software can accurately output stimulus waveform to record cell response in real time , while responding to significantly increase the speed , reduced memory consumption , to meet the large amount of data operation . Than PClamp4.0 version of the software , to better meet the needs of the electrophysiological experiments .

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CLC: > Industrial Technology > Automation technology,computer technology > Computing technology,computer technology > Computer software > Program design,software engineering > Software Engineering > Software Development
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