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The Study on Related Clinical Factors of Hypoxic Ischemic Encephalopathy

Author: ChenMin
Tutor: YangHuiMin
School: Henan University of Science and Technology
Course: Internal Medicine
Keywords: Hypoxic-ischemic encephalopathy Protective factors Risk factors Discharged outcome Epidemiology
CLC: R722.1
Type: Master's thesis
Year: 2010
Downloads: 57
Quote: 0
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Abstract


Objective To investigate the impact of HIE incidence and discharge from the outcome of relevant factors, the facts normative interventions to improve the Luoyang region perinatal care and to develop suitable to provide a reference to further reduce the region's HIE incidence and improve HIE suffering children discharged outcome. Full inspection on the basis of the available literature, the method chosen may HIE incidence factors related to the preparation of questionnaire, the questionnaire includes: general admission ② the mothers maternity situation ③ the neonatal period ④ ① social factors physical examination the ⑤ discharged outcome. Take, while at the same time period, the control of the same age with normal weight newborn. Hospitalized the River Branch YiFuYuan received the 206 neonates with HIE and 211 normal newborns epidemiological investigation SPSS17.0 statistical analysis software to conduct statistical analysis of the survey results, the first data χ2 test, t test and rank sum test, and then to HIE incidence or not and discharged the outcome of the situation as the dependent variable, test meaningful clinically relevant factors as independent variables in multivariate logistic regression analysis, come to affect the HIE the incidence and discharged outcome risk factors and protective factors. Time of the survey: October 2006 to September 2009 results were distributed in normal children and children with questionnaire 225 points, for a total of 450 copies, 417 were recovered qualified questionnaire, with a pass rate of 92.67 percent. Univariate analysis showed that factors HIE incidence: children with gender, place of residence, parents 'occupation, parents' education level, maternal height, mother of anemia, placental abnormalities, premature rupture of membranes, preeclampsia, prenatal care, oxytocin , the number of births, gestational age, birth weight, labor, mode of delivery, the umbilical cord abnormalities, amniotic fluid volume, amniotic neonatal lung disease. Multivariate Logistic regression analysis showed that the HIE incidence of related factors: mother education level, maternal anemia, preeclampsia, placenta circumstances, the umbilical cord circumstances, meconium, labor, oxytocin, gestational age, etc.. Discharged outcome Univariate analysis found: placental abnormalities, the number of births, birth weight, birth process, 1-minute Apgar score, a 5-minute Apgar score, reflection, hospitalization time, hospitalization days and its prognosis. Multivariate Logistic regression analysis showed that the discharge and HIE outcome-related factors: the placenta situation, the number of births, the birth process, the situation of the umbilical cord, birth weight, 5-minute Apgar score, number of days of hospitalization. HIE incidence Conclusion ① influence factors: abnormal meconium, preeclampsia, labor, placental abnormalities, abnormal umbilical mother anemia six factors for the onset of the major risk factors; mother's education level, the use of oxytocin, gestational age normal 3 factors as the main protective factors. Major risk factor for the factors affect ② discharged outcome: placental abnormalities, multiple births, abnormal labor, umbilical cord abnormalities four factors for the influence of HIE discharged outcome; normal weight children, 5-minute Apgar score greater than 7 points, hospital days seven days, three factors as the main protective factors. ③ HIE disease and its prognosis is closely related to the prenatal, intrapartum, and postpartum clinical multiple factors and social factors. Improve the quality of population culture, in particular, focus on improving the level of women's culture is a major significance for the prevention of HIE incidence; positive good perinatal care, and strengthen the health education focusing on backward rural areas and high-risk pregnant women; to improve maternity pediatric diagnosis and treatment capacity to reduce premature birth the incidence of birth trauma and perinatal asphyxia; aggressive treatment can significantly improve the prognosis of the disease, reduce the incidence of sequelae and improve the quality of life in children.

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CLC: > Medicine, health > Pediatrics > Newborns, premature children disease > Neonatal disease
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