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A Study of the Effect of Pqs on the Content of GFAP and S-100β in the Serum of Cerebral Ischemia Rats

Author: LiuKun
Tutor: SuYunMing；GuanLiXin
School: Heilongjiang University of Traditional Chinese Medicine
Course: Chinese medicine
Keywords: Panax quinquefolius saponin Focal cerebral ischemia GFAP S-1OOβ
CLC: R285.5
Type: Master's thesis
Year: 2010
Downloads: 36
Quote: 0
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Abstract


Objective: To study panax quinquefolius saponin (PQS) for the protection of experimental cerebral ischemia Yang , progress to explore its mechanism . : Intraluminal rat model of focal cerebral ischemia using enzyme-linked immunosorbent assay PQS on the protein content of the serum GFAP.S-100β , and observe the defects of neurological function before and after the treatment of the PQS caused behavioral changes observed by HE staining and the MCAO rats morphological changes in order to judge PQS neuroprotective effects on cerebral ischemia . Results : PQS can improve the symptoms of neurological deficit , cerebral ischemia pathomorphological changes significantly reduced , lowering the blood GFAP and S-100β protein content . Conclusion : PQS has a protective effect on cerebral ischemia .

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