Dissertation > Excellent graduate degree dissertation topics show

Expressions of IL-6 mRNA and Protein in Gum with Periodontitis

Author: ZhangTianFu
Tutor: GaoWenXin
School: Jilin University
Course: Clinical Stomatology
Keywords: periodontitis interleukin-6 gene expression immunohi-stochemistry
CLC: R781.4
Type: Master's thesis
Year: 2006
Downloads: 107
Quote: 1
Read: Download Dissertation

Abstract


Many cytokines play important roles in pathogenic process of periodontitis,among them IL-6 has close relation with periodontitis. IL-6 can not only inducethe disruption of periodontal tissue directly, but also affect the process ofinflammation reaction and immune reaction further, and aggravate the disruptionof periodontal tissue. The production and effects of IL-6 are regulated by manyfactors. The determination of IL-6 and inhibition of the secretion and disruptioneffect have certain clinic value in diagnosis and treatment of periodontitis.In this experiment, the expressions of IL-6 mRNA and protein in normalgum and lesion gum in patients with periodontal disease were detected withimmunohistochemistry in order to study the relationship between IL-6 andpathogenic mechanism. So the effective method to regulate the IL-6 could befound to provide theoretical basis for diagnosis and therapy of periodontitis. Theresults showed that the expression levels of IL-6 mRNA and protein in normalgum tissues were lower, the expression levels of IL-6 mRNA and protein inpatients with periodontitis were significantly higher than those in normalcontrol (P<0.01). The results indicated that IL-6 played an important role inpathogenic process and had closer relation with periodontits. To detect theexpressions of IL-6 mRNA and protein in gum can be used to diagnoseperiodontitis promptly and correctly, and guide therapy, judge curative effectsand prognosis.

Related Dissertations

  1. Study on Synthesis and Physiological Function of N-carbamoyl-glutamate,R914
  2. Coparative Analyses of Carbon and Nitrogen Metabolism of Flue-cured Tobacco Growing in Henan and Yunnan,S572
  3. Comparison of Gene Expression Data Cluster Methods and Gene Network Construction for Phytophthora Sojae Genes,S435.651
  4. Research on Characteristics of Growth, Development and Material Metabolism of Flue Cured Tobacco Leaves in Huili, Sichuan,S572
  5. Studies on Extracting Mitochondrial DNA and Gene Expressions in Brassica Napus L,S565.4
  6. Roles of MMP-7 and Lysozyme in the Pathogenesis of Ulcerative Colitis Induced by DSS in Balb/c Mice,S858.91
  7. The Study of Kisspeptin/GPR54 System on the Reproductive Regulation in the Hen’s Hypothalamus-Pituitary-Ovary Axis,S831
  8. Study on the Digestive Tube During the Embryonic Stage of Gushi Chicken,S831
  9. The Effects of Don on Proliferation, Differentiation, and Apoptosis of Chondrocytes in Chicken,S858.31
  10. A Comparative Study of prawns, crabs, Spiroplasma disease immunohistochemistry and pathology,S945
  11. Expression of WW Domain Containing Oxidoreductase Gene in Cholangiocarcinoma and Its Effect on the Biological Behavior of Cancer Cell Line QBC939,R735.8
  12. Expressions of PRL-3 and p27 in Gastric Carcinoma and Their Clinical Significance,R735.2
  13. Expression of hnRNP A2/B1 and p21WAF1 Proteins in Lung Cancer and Their Clinical Significance,R734.2
  14. The Effects of RIP on the Immune Function of Renewal Rats Without Colostrums,S853.7
  15. Study on the Expression and Correlation of Metallothionein and Matrix Metalloproteinase-2 in Non-small Cell Lung Cancer,R734.2
  16. Molecular Cloning, Sequence nad Expression Analyses of Two Transcription Factors ZmC4HC3 and ZmNAC,S513
  17. Expression and Their Significance of Apoptosis Regulatory Factors Survivin、XIAP and c-Jun、NF-κB in Epithelial Neoplasm of Ovary,R737.31
  18. Expression and Clinical Significance of Survivin and YAP in Cervical Carcinoma,R737.33
  19. Expression and Clinical Significance of PTEN and Caspase-7 in Gastric Cancer and Precancerous Lesion,R735.2
  20. Study on Expression of MMP-8 on Experimental Periapial Periodontitis is Infected by Enterococcus Faecalis,R781.34
  21. The Regulatory Role of Proliferation and Apoptosis of ERK1/2 and JNK Signaling Pathways in Eight Liver Cell Types during Rat Liver Regeneration,Q418

CLC: > Medicine, health > Oral Sciences > Oral medicine > Periodontal disease
© 2012 www.DissertationTopic.Net  Mobile