|
Winged stems Saussurea (Saussurea cauloptera) Department Saussurea , Asteraceae (Compositae) is a perennial herb (Saussurea DC) , mainly located in China 's northwest mountains . Saussurea genus of about 400 species distributed in Asia and Europe , about 264 kinds of our country . Saussurea are a wide variety of plants , many species are used as traditional Chinese medicine used to treat traumatic bleeding , gynecological disease , and rheumatoid arthritis . The winged neck Saussurea chemical composition has not been reported , the papers collected from Qinghai Province wings neck wind Saussurea whole grass chemical composition of petroleum ether depth study , to extract by a variety of chromatographic methods isolated 36 compound, and apply modern variety of spectroscopic (1D NMR, 2D NMR, HR-ESI-MS, EI-MS, IR, UV , etc.) as well as the comparison with the known compounds or literature data including three identified 30 terpenes, terpene , sesquiterpene steroidal structure of the compound . 3 for a new structure of compounds , their structure is determined to be : 7α- hydroxy -gerin (2), 8β- desacetyl -gerin (3), 8 (17), 13 - diene -3α-hydroxy -16 , 15 - corresponding Helianthemum lactone ( 9) . Some eucalyptus alkyl sesquiterpenes anticancer activity , the results show that these compounds have a good role in the inhibition of gastric tumor cells (SGC-7901) . The papers also an overview of the Biological Activity of eucalyptus alkyl sesquiterpene compounds . The results of this thesis research, structure-activity relationship of the active ingredients of traditional Chinese medicine in China , as well as new drug screening provides valuable scientific basis .
|