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Objective:To observe the ginsenoside Rgl in rat experimental Parkinson’s disease neuronal oxidative injury, and to investigate the protective effect on neurons.Methods:This study used brain-dimensional positioning technology, application of 6-OHDA striatal injection to establish a rat model of Parkinson’s disease, Parkinson observed in blood superoxide dismutase (SOD), malondialdehyde (MDA), lactate dehydrogenase (LDH) levels, and neurological function scores and pathological changes in the use of ginsenoside Rgl against oxidative damage as a model of Parkinson drugs treatment and prevention of experimental rats.Result:Ginsenoside Rg1 can significantly reduce the rate of rat behavior disorder, Parkinson’s can significantly reduce the serum MDA, LDH content and increase the activity of SOD significantly increased the brain cells, SOD activity and decreased MDA content.Conclusion:Ginsenoside Rg1 can improve the neurological behavior of Parkinson’s model rats, decreased apomorphine-induced rotation, ginsenoside Rg1 can reduce oxidative damage to the striatum increased the levels of SOD activity, decreased MDA, LDH levels, that ginsenoside Rg1 is an effective medication against oxidative stress can play a role in the treatment of Parkinson’s.
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