Dissertation > Excellent graduate degree dissertation topics show

The Clinical Research on the Treatment of Ovarian Tumour by Lichongshengsuiyin Combined with Chemotherapy

Author: Cheng
Tutor: HanFengJuan
School: Heilongjiang University of Traditional Chinese Medicine
Course: Chinese medicine
Keywords: Ovarian cancer Chemotherapy after surgery Tianshenjing Jianpi Xiaozheng Li chong shengsuiyin Attenuation and synergism
CLC: R273
Type: Master's thesis
Year: 2010
Downloads: 37
Quote: 0
Read: Download Dissertation

Abstract


Objective:access lichongshengsuiyin Combined TC in the treatment of ovarian cancer after chemotherapy in patients with short-term clinical efficacy and attenuated chemotherapy medicine synergies.Methods:50 ovarian cancer patients needed chemotherapy were randomly divided into treatment group (TCM+chemotherapy) and control group (chemotherapy alone), each 25. Chinese medicine symptom effect scoring, physical score, quality of life score, and the toxicity and tumor markers CA125 to assess changes in values of Lichongshengsuiyin combine TC in the treatment of ovarian cancer patients after therapy.Results:1. In improving the symptoms of TCM in the treatment group the total effective rate (84.00%) was significantly higher, compared with the control group (48.00%). there were significant differences (P<0.01). It shows treatment group patients in the TCM treatment syndromes exceed the control group patients (P<0.05).2. Karnofsky score of the treatment group before the treatment compared with after the treatment is no significant difference (P>0.05). Karnofsky score of the control group before the treatment compared with after the treatment is no significant difference (P>0.05). After treatment, Karnofsky score statistical comparison, there are significant differences (P<0.05), shows the treatment group exceed the control group in physical condition.3. QOL points of the treatment group before the treatment compared with after the treatment is no significant difference (P>0.05). QOL points of the control group before the treatment compared with after the treatment is significant difference (P>0.05). Statistical comparison between the two group after treatment, there were significant differences (p<0.01), showed that the treatment group can significantly improve the quality of life of the chemotherapy patients.4. Toxicity and safety indicators show:WBC, platelet count, nausea, vomiting, hair loss, blood urea nitrogen values of the treatment group compared with the control group is significant difference (P<0.01). Granulocyte of the treatment group compared with the control group is statistically significant difference (P<0.05), and the intervention rate of the treatment group compared with the control group is significant difference (P<0.01), showed that the treatment group can reduce chemotherapy-induced bone marrow suppression, gastrointestinal reactions, renal damage and other side reaction.5. The changes in tumor markers-CA125 of the treatment group before the treatment compared with after the treatment is significant difference (P <0.005). The changes in tumor markers-CA125 of the control group before the treatment compared with after the treatment is statistically significant difference (P<0.05). the statistical comparison between the two treatment group after the treatment is significantly different (P<0.05), showed that the treatment group and control group can effectively reduce the value of CA125, but the decrease speed and range of CA125 in treatment group even more apparent.Conclusion:1. LiChongShengSuiYin can improve the life quality of ovariancancer patients with postoperative chemotherapy.2. LiChongShengSuiYin can prevent and reduce chemotherapy-induced bone marrow suppression, gastrointestinal reactions, renal damage and other side effects.3. LiChongShengSuiYin can increase the role of chemotherapy drugs kill cancer cells.

Related Dissertations

  1. Expression and Their Significance of Apoptosis Regulatory Factors Survivin、XIAP and c-Jun、NF-κB in Epithelial Neoplasm of Ovary,R737.31
  2. Effects on Telomere Length of Epithelial Ovarian Cancer by Chemotherapy,R737.31
  3. Recurrent Ovarian Cancer Surgery Again with Surial Analysis of Relevant Factors,R737.31
  4. Expressions and Relationships of PI3K/AKT and Apoptosis Related Regulation Factors in Epithelial Ovarian Tumors,R737.31
  5. Inhibition of CD24 Expression to Induce Anoikis in Ovarian Cancer Cells,R737.31
  6. Analysis of the Relationship between Endometriosis and Ovarian Cancer,R711.71
  7. Based graphene material , a Novel DNA biosensor,TP212.2
  8. The Expressions and Signifcance of Survivin and BAG-1 in the Epithelial Ovarian Cancers,R737.31
  9. Accuracy of FISH for 3q26 Gains as a Screening Marker in Cervical Cancer,R737.33
  10. The Study of E-cadherin Gene Promoter Demethylation in Nude Mice Burdended-ovarian Cancer,R737.31
  11. Effects of Apigenin on Trail-induced Apoptosis in Human Ovarian Cancer CoC1 Cells,R737.31
  12. The Influence and Mechanisms of Mythylglyoxal on Growth and Apoptosis of Human Ovarian Cancer Cells HO8910,R737.31
  13. Surveys of Short-term Efficacy of TP Therapeutic Regimen Applied to 81 Cases of Ovarian Cancer Patients,R737.31
  14. Breast and ovarian cancer BRCA1 gene mutation,R737.9
  15. Effects of RNAi-mediated Endoglin Gene Silencing in Endothelial Cells of Ovarian Carcinoma,R737.31
  16. Study on the Mechanism of FSH to Cell Proliferation and Invasion Mediated by PI3K/Akt/NF-κB in Human Epithelial Ovarian Cancer,R737.31
  17. Medical Treatment of Resistant or Recurrent Epithelial Ovarian Cancer--Cl Inical Analysis of 33 Patients with Recurrent or Resistant Epithelial Ovarian Cancer,R737.31
  18. A Meta-analysis on the Effect of Laparoscopy Versus Laparotomy Treatment of Early Ovarian Cancer,R737.31
  19. Association of p73 and MDM2 Polymorphisms with the Risk of Epithelial Ovarian Cancer,R737.31
  20. Study on the Association of Snps of Vegf Gene with the Risk of Epithelial Ovarian Cancer,R737.31

CLC: > Medicine, health > Chinese Medicine > TCM oncology
© 2012 www.DissertationTopic.Net  Mobile