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Study on the Relevance between the Infection of Ureaplasma Urealyticum and Reproductive Tract Bacterical Infection

Author: LiuHuiBo
Tutor: ZhengHua
School: Jilin University
Course: Dermatology and Venereology
Keywords: Ureaplasma urealyticum Reproductive Tract Infection Relevance Candida albicans Coagulase-Negative Staphycoccus
CLC: R446.5
Type: Master's thesis
Year: 2012
Downloads: 76
Quote: 0
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Abstract


The genital tract is an open chamber way. It has a complex ecologicalenvironment. Normally bacterium in the genital tract restrict each other in orderto maintain certain balance. But in some cases they can cause dysbacteriosis, forexample inappropriate vaginal cleaning, sex chaos and broad-spectrumantibiotics be abused etc. In clinical work, we found that repeated attacks ofReproductive tract infection and the mix infection of pathogens are verycommon. Ureaplasma urealyticum infection and dysbacteriosis are twoimportant reasons that can cause the reproductive tract infection. To study therelationship between Uu and bacterium infection, We selected80men and71women who meet the conditions of the test, and gave these volunteers Uu testingand Bacteria culture identification. Preliminary discuss the relationship in thedifferent environment of male urethra and feminine vagina.First do notice no extra bacterial contamination when collecting specimens.Inoculated the secretion (men from urethral and women from cervix) into the Uuliquid medium, then put the medium under the temperature between35to37centigrade for48hours and get the results. If the chlour of the medium changedfrom orange to red and the liquid was clear, We marked it positive, otherwisenegative. Inoculated the secretion (men from urethral and women from the vaultof vaginal) respectively into the blood, Maikangkai and Sabouraud’s AGARplates and then put the mediums under the temperature between35to37centigrade for48hours. Observed the growth of bacteria. Later picked appropriate colonies for gram stain making the preliminary screening of positiveand negative bacteria. Use the French VITEK TWO Automatic instrument forbacteria identification.The results: in women, There were40Uu positive patients (56.34%). Andthe mixed infection of Uu and other pathogens: Uu and CNS(coagulase-negativestaphycoccus)(4cases); Uu and Streptococcus viridans(7cases); Uu andEscherichia coli (5cases); Uu and E.faecalis (8cases); Uu and corynebacteria(3cases); Uu and Candida albicans (16cases). The positive rate of the Candidaalbicans together with Uu positive group was far higher than the Candidaalbicans positive while Uu was negative group. Χ~2=4.778,P=0.029(P<0.05),Statistical significance was found between the two groups. In men, There were36Uu positive patients (45%). The mixed infection of Uu and other pathogensin men:Uu and CNS (8cases); Uu and Streptococcus viridans(5cases); Uu andE.faecalis (4cases); Uu and corynebacteria (5cases); Uu and Candida albicans(6cases); Uu and Neisseria gonorrheae (4cases). The positive rate of the CNStogether with Uu positive group was far lower than the CNS positive while Uuwas negative group. Χ~2=4.698,P=0.03(P<0.05),Statistical significance wasfound between the two groups.We can draw the following conclusions: Uu and Candida albicans havecertain relations in feminine vagina infections; The infection of Uu canencourage the infection of Candida albicans; Uu and CNS have negativecorrelation in male urethra infections; CNS takes part in transformation and end-result in some men NGU patients.

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