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The Evaluation of Left Ventricular Structure and Function and Its Influence Factors in Restarting Dialysis Patients after Kidney Allograft Loss

Author: LeiWenHua
Tutor: ChenJiangHua
School: Zhejiang University
Course: Internal Medicine
Keywords: Kidney allograft loss Left ventricular structure Left ventricular function Anemia Malnutrition Micro-inflammation
CLC: R459.5
Type: Master's thesis
Year: 2013
Downloads: 2
Quote: 0
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Abstract


Objective:To evaluate the left ventricular structure and function in restarting dialysis patients after kidney allograft loss and understand its related factors.Methods:The case group is kidney allograft loss patients who restart hemodialysis, and the control group is the patients with end-stage kidney disease without renal transplantation. Left ventricular structure and function indexs as well as blood assay index were measured. The time is before hemodialysis,6months and1year after hemodialysis.Results:Before hemodialysis, the level of EF, FS, eGFR in case group is higer than the control group, and the Scr, BUN of case group is lower(P<0.05). After hemodialysis, these indexs have no significant difference between two groups (P>0.05). The CRP of case group is always higher than of control group (P<0.05). The blood pressure, left ventricular structure, diastolic function, anemia indexs, nutritive indexs, calcium, phosphate, PTH of two goups have no significant difference before hemodialysis (P>0.05). After6months and1year of dialysis, the Hb, Alb, calcium of two groups increse (P<0.05). The level of Systolic pressure, LVDd, LVPWd, LVM, LVMI, CTR decreases after hemodialysis and the CTR of control group is obviously lower than those before hemodialysi (P<0.05). However, These indexs of case group have no significant change (P>0.05)Conlusion:LVH is very common in ESRD patients. After1year of hemodialysis, the improvement of hypertension, anemia, malnutrition and microinflammation is not so obvious in kidney-allograft-Loss patients. And the LVH is more diffucult to correct. However, the LVH of ESRD patients without kidney transplantation can be reversed to some extent. Therefore, once renal allograft dysfunction is founded, the indexs of hypertension, anemia, malnutrition and microinflammation should be cared to decrease the morbidity and mortality of CVD.

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