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Studies on Synthesis of3-substituted Benzofuran Derivatives via Electrophilic Cyclization under Green Conditions

Author: HanJiangSheng
Tutor: ZhongPing
School: Wenzhou University
Course: Organic Chemistry
Keywords: green chemistry electrophilic cyclization one-pot reaction suzuki Reaction benzofuran
CLC: O626.11
Type: Master's thesis
Year: 2013
Downloads: 13
Quote: 0
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Abstract


This thesis mainly studied on the synthesis of3-substituted benzofuranderivatives from2-alkynylanisoles via electrophilic cyclisation under greenconditions. The contents mainly consist of the following three parts.Part Ⅰ: In this part a summary of recent progress in the study of thesynthesis of3-substituted benzofuran derivatives from2-alkynylanisoles viaelectrophilic cyclisation reaction was made.Part Ⅱ: In this part the synthesis method of3-chalcogen benzofurans vianonmetal catalysts electrophilic cyclisation under solvent-free conditions or inwater was developed.Part Ⅲ: In this part a one-pot reaction to synthesize2,3-diarylbenzofuranderivatives via electrophilic cyclization then palladium-catalyzed suzukireacton in water was developed.

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CLC: > Mathematical sciences and chemical > Chemistry > Organic Chemistry > Heterocyclic compounds > Five heterocycles containing a single different atoms > Oxa -mao ( furans) family
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