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The Effects of Atorvastatin on Left Atrial Structure and Fucntion in Patients with Atrial Fibrillation After Radiofrequency Catheter Ablation

Author: JiangQiong
Tutor: LiJinGuo
School: Fujian Medical
Course: Medical Imaging and Nuclear Medicine
Keywords: Radiofrequency ablation Paroxysmal atrial fibrillation Left atrial function Atorvastatin Echocardiography
CLC: R541.75
Type: Master's thesis
Year: 2010
Downloads: 49
Quote: 0
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Abstract


Purpose . Echocardiography observe the changes in the structure and function of the left atrial linear ablation of atrial fibrillation in patients with pulmonary vein before and after left atrial echocardiography explore atorvastatin Structure and Function of the left atrium in patients with atrial fibrillation selected April 2008 to March 2009 , the Union Hospital of Fujian Medical University, Department of Cardiology, diagnosis of patients with paroxysmal atrial fibrillation 24 cases in the control group underwent circumferential pulmonary vein left atrial linear ablation ( CPVA ) before surgery, are I blank control . 2009 to 2010 CPVA in line with paroxysmal atrial fibrillation in 32 patients for the experimental group , preoperative and postoperative intervention to atorvastatin . Patients in the preoperative and postoperative one day , after 3 days , after 5 days , after 7 days , one month after the line echocardiography , image archiving , detection of the patient's left atrial diameter , late diastolic peak A peak velocity ( VA ) , left atrial filling fraction ( AFF ) , left atrial ejection force ( AEF ) , mitral annulus velocity ( Va ) , the results were statistically analyzed. Results 1. Reduced anteroposterior diameter of the left atrium , the left and right diameter , vertical diameter of postoperative month compared with preoperative ( P lt ; 0.01 ) Experimental group and control group by the mean value point of view , the experimental group decreased slightly stronger than the control group , but between two groups no significant difference ( P GT ; 0.05 ) VA , AFF , AEF postoperative were significantly lower than preoperative ( P lt ; 0.01 ) to one month after surgery is still lower than the preoperative level ( P lt ; 0.01 ) Experimental group and the control group, by the mean point of view , the experimental group was slightly higher , but between two groups no significant difference ( P GT ; 0.05 ) . , The experimental group and the control group after Va were significantly lower than the preoperative levels ( P lt ; 0.01 ) to one month after surgery is still lower than the preoperative level ( P lt ; 0.01 ) . Experimental group and the control group, by the mean point of view , the experimental group was slightly higher , but between two groups no significant difference ( P GT ; 0.05 ) . Conclusion CPVA surgery treatment of paroxysmal atrial fibrillation successful , left atrial structural remodeling can be reversed , left atrial function after surgery significantly reduced in the short term can not be restored to the preoperative level . Alto atorvastatin in patients with paroxysmal atrial fibrillation , the short-term impact on the structure and function of the left atrium is not obvious .

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CLC: > Medicine, health > Internal Medicine > Heart, blood vessels ( circulatory ) disease > Heart disease > Arrhythmia > Atrial fibrillation and atrial flutter
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