Dissertation > Excellent graduate degree dissertation topics show

The Application of LPME Coupled with GC-MS in Some Foods and Drugs Analysis

Author: QiAiMing
Tutor: MaoLiQiu
School: Hunan Normal University
Course: Organic Chemistry
Keywords: Droplets of liquid microextraction (SDME) Hollow fiber membrane liquid-phase microextraction (LPME-HF) Chromatography - mass spectrometry using (GC - MS ) Food and Drug White spirit
CLC: O657.63
Type: Master's thesis
Year: 2009
Downloads: 283
Quote: 1
Read: Download Dissertation

Abstract


In the pharmaceutical and food analysis, liquid-liquid extraction classic mature one of the sample pre-treatment technology, but there is a complicated operation, time-consuming, a large amount of solvent, easy loss of the sample, the larger issues such as harm to the environment and people. Simple, fast, efficient, green, less solvent sample preparation and pre-treatment technology has been the focus of attention of the analysis of workers. Liquid microextraction (LiquidPhase Microextraction, LPME) to overcome the disadvantages of traditional liquid - liquid extraction technology to adapt to the requirements of the development of modern analytical science, is a set of extraction, purification, enrichment, in one injection, environmentally friendly sample pre-treatment technology. The liquid-phase micro-extraction technology including droplets of liquid microextraction (Single Drop Microextraction SDME) and hollow fiber membrane liquid-phase microextraction (Hollow Fiber Liquid Phase Microextraction LPME-HF). Droplets of liquid phase micro extraction technique is simple, inexpensive, fast and environmentally friendly, but poor physical stability of the droplets of liquid phase microextraction aerosols, so people began to use hollow fiber membrane liquid-phase microextraction protection droplets. Application hollow fiber membrane liquid-phase microextraction considered the latest developments of the droplets of liquid phase microextraction solve the traditional liquid-liquid extraction operations were time consuming, easy to emulsify and require a large number of samples and the droplets of liquid phase microextraction aerosols physical poor stability and other issues. In this paper, the droplets of liquid phase microextraction and hollow fiber membrane liquid-phase microextraction and gas chromatography - mass spectrometry analysis determined in Drug and Food phthalates and paraben esters and liquor, in ethyl n-hexyl, and achieved good extraction effect, the droplets of liquid phase microextraction and hollow fiber membrane liquid-phase microextraction of the Food and Drug Analysis method has great application prospects. The main contents are: droplets of liquid phase microextraction and gas chromatography mass spectrometry analysis of phthalates in medicines and paraben ester, and the various factors affecting the extraction were investigated, such as the type of solvent , solvent amount, the depth of the micro-droplets in the sample, stirring rate, extraction time of the selection, etc., to determine the optimum extraction conditions will be applied to the detection of the actual liquid medicine. 2, hollow fiber membrane liquid-phase microextraction gas chromatography - mass spectrometry analysis of phthalates in medicines and paraben ester, stirring speed and extraction time on the impact of the hollow fiber membrane liquid-phase microextraction optimization and Determination for drug analysis. 3, hollow fiber membrane liquid-phase microextraction and gas chromatography - mass spectrometry analysis of food paraben esters investigated the extraction of various factors such as the extraction solvent type, extraction time, ionic strength extraction effect and will be used for the detection of milk powder, soybean milk powder, coconut powder analysis. Hollow fiber membrane liquid-phase micro-extraction technology and conventional analysis with gas chromatography - mass spectrometry liquor ethyl n-hexyl, on a variety of factors that affect the hollow fiber membrane liquid-phase microextraction, such as the type of extraction solvent, extraction time and stirring speed optimization, will be used for the detection of the n-hexyl ethyl Luzhou-flavor liquor.

Related Dissertations

  1. The Qionglai liquor industry competitive analysis,F426.82
  2. S Food and Drug Administration Performance Evaluation,F203
  3. The Design and Implementation of Food and Drug Administration and Management System for Drug Administration of Kuiwen District,F203
  4. The Research on Promblems of Food and Drug Administration,F203
  5. Xicheng District, medication safety electronic monitoring system,TP311.52
  6. New Food and Drug Safety Emergency Management,F203
  7. RFID-based Pharmaceutical Packaging Information Management System,TP315
  8. The Study on the Civil Servant Performance Assessment of Food and Drug Regulatory System of Xinjiang,D630.3
  9. A Research on Corporate Social Responsibility Based on Promotion of Business Performance,F270
  10. Design and Implementation of the MVC Model Based Operational Management System of Food and Drug Supervision,TP311.52
  11. Study on Current State of Equipment Resources of State Food and Drug Administration,F203
  12. Food & Drug Surveillance Performance Appraisal and Application Research,F203
  13. Federal Government U.S. Food and Drug Control of Public Policy Research,DD912.1;D971.2
  14. The Innovation of Food and Drug Administration System in China,F203
  15. Electronic Nose: Studies on Gas Sensor Arrays, Systems and Its Applications,TP212
  16. A Study of Visualization Bionic Olfactory System for the Detection of Chinese Liquor,TS261.7
  17. Research on Marketing Strategy of Shandong Lanling Co.Ltd,F426.82
  18. Research on Chinese Alcohol by Gas Chromatographic/Mass Spectrometric Analysis of Nonvolatile Compounds,TS262.3
  19. Study on Stability of Fatty Acid Esters in Alcohol Liquor and Its Application,TS261.7
  20. Multiple ( re ) solvent peak suppression method comparison and liquor NMR determination,O657.2

CLC: > Mathematical sciences and chemical > Chemistry > Analytical Chemistry > Instrument analysis ( physics and physical chemistry ) > Mass Spectrometry
© 2012 www.DissertationTopic.Net  Mobile