Dissertation > Excellent graduate degree dissertation topics show

Study on the Extraction of Natural β-Carotene and the Development of Its Soft Capsule Product

Author: LiYaPing
Tutor: ChengWeiDong
School: Shihezi University
Course: Agricultural Products Processing and Storage
Keywords: Natural β-carotene Response Surface Methodology Biological activity Soft Capsule Stability
CLC: R151
Type: Master's thesis
Year: 2009
Downloads: 66
Quote: 0
Read: Download Dissertation

Abstract

Natural β-carotene has anti-cancer, enhance immunity, slow aging and other health functions, extract and formulation development in the areas of health and medical gaining attention. To develop new products, improve the added value of carrots for the purpose of microwave-assisted extraction of β-carotene extraction technique to explore the natural β-carotene soft capsule production process parameters and further biological activity and stability sexual system. The results are as follows: (1) select Name 1 Canada carrot as raw materials, including β-carotene content of up to 252.20mg/100g material pretreated sifted through a 80 mesh sieve, in order to effectively absorb microwave temperature difference , thereby enhancing the extraction effect, pre-extracted with 75% ethanol impregnation process. (2) with ethyl acetate as the solvent, the use of the preferred experiment and response surface analysis of single factor test design, the use of microwave-assisted extraction of the optimal parameters of the β-carotene: microwave power 386W, time 7min liquid material than 22mL / g β-carotene extraction reached 0.5587mg / g; soybean salad oil as the solvent, the single factor the preferred experiment and response surface analysis of the trial design, optimal parameters of microwave-assisted extraction of β-carotene: microwave power 394W, time 6min, liquid to solid ratio of 43 mL / g, the amount of beta-carotene extracted 0.399mg / g. With ethyl acetate as the solvent, compared to the soybean salad oil as solvent, the amount of the solvent to save 1/2, can significantly improve the natural β-carotene extraction amount. (3) through the process of natural beta-carotene soft capsule, OK soft capsule optimal parameters of plastic processes, pelleting process: chemical glue temperature of 60-70 ° C, time 4 hours of plastic, vacuum degree -0.08-0.06Mpa; the pelleting process parameters: spray body control temperature 38-45 ℃, contents Temperature lt; 40 ° C, the glue temperature 55-65 ° C. And products of microorganisms, heavy metals, disintegration time limit, acid value, net content indexes were determined. (4) through the high temperature, high humidity and light irradiation conditions affecting factor test, no significant changes in all the indexes of natural β-carotene soft capsule, are within the acceptable range; samples of three batches of soft capsules 3 months at room temperature the leave sample test results show that the sensory indicators, microbial indicators and the main physical and chemical indicators did not change significantly. This indicator meets the requirements of the national Ministry of Health issued a health food. (5) the use of colorimetric natural β-carotene soft capsule of NO ₂ ^{- ,. OH, O ₂ ^{- and DPPH radical scavenging capacity, the same concentration, the ability to clear the O ₂ ^{- natural β-carotene soft capsule is the strongest, followed by NO < sub> 2 ^{- and DPPH radical, clear the weakest. OH. VC contrast, in the selected concentration range, the natural β-carotene soft capsule with VC quite clear the effect of NO ₂ ^{- , free radical scavenging effect than VC bit weak, but in concentrations of less than 54ug/mL OH clearance rate is higher than VC. (6) by the MTT assay and microscope observation, the inhibition of the natural β-carotene soft capsule of mice fibrosarcoma S180 cells, but the inhibitory effect was not significant in the selected concentration range, its inhibition mechanism needs further study.}}}}}

Related Dissertations

CLC: > Medicine, health > Preventive Medicine,Health > Nutrition, hygiene,food hygiene > Nutrition
© 2012 www.DissertationTopic.Net Mobile