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On the Risk Factors of Anastomotic Leakage after Colorectal Carcinoma Resection

Author: QinGuangYuan
Tutor: HuangGuiLin
School: Shihezi University
Course: Surgery
Keywords: Colorectal Cancer Anastomotic leak Surgery
CLC: R735.37
Type: Master's thesis
Year: 2010
Downloads: 37
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Abstract


Objective: To investigate the possible cause colorectal cancer postoperative anastomotic leakage reasons, to provide recommendations for the prevention of the occurrence of colorectal anastomotic leakage and provide technical support for colorectal cancer standardized treatment. Methods: From January 1999 -2009 in January in the First Affiliated Hospital of Shihezi University School of Medicine and the Hunan Provincial Tumor Hospital ventrolateral Division One parallel enteric anastomosis underwent surgery in patients with colorectal cancer, the medical records of 826 cases, of which 70 cases of postoperative anastomotic fistula, the incidence was 8.5%, retrospective analysis of risk factors for anastomotic leakage occurred. Results: anastomotic leakage occurred in 70 cases in the group of 826 cases of surgical patients, the rate was 8.5%. All clinical data by gender into male group and female group 2; into obese according to body type, the normal group and the weight loss group 3 group; diabetes divided into group 2 diabetic group and diabetic group combined according to whether the merger; Press surgery divided into, MD, deputy director of the group and chief physician group 2 group; whether by surgery using fibrin glue into unused group and group 2; according to whether or not to use a stapler surgery divided into 2 groups; unused groups and use group according to whether divided into non-smoking and alcohol group alcohol addiction and smoking and alcohol group 2; normal group and low hemoglobin hemoglobin is normal divided into 2 groups; different surgical approaches taken by the location of the tumor points right colon resection group , transverse colon resection group, the left colon resection and Dixon surgery group 4 group; Dukes stage into Phase A group phase group B, C phase group and D Group 4; bowel preparation is divided into good group, and the difference between 2 groups; anastomotic blood supply is divided into 2 groups organizations often group of blood supply and blood supply; anastomotic tension divided into 2 groups tension normal tension; serum albumin levels divided into 2 groups; normal group and hypoproteinemia group by age into age lt; 60-year-old group and age ≥ 60 age group; divided into operative time is less than the average surgery time group and greater than average surgery time group 2. Multiple comparisons between the χ2 test and multiple sample rate, logistic regression analysis of risk factors associated with anastomotic leakage after colorectal cancer surgery found that anastomotic leakage occurred with the patient's gender, body size, whether associated with diabetes, whether or not to use the stapler surgery, usually alcohol addiction, hemoglobin, tumor location, tumor stage, bowel preparation situation, anastomotic blood supply, anastomotic tension, serum albumin level, age, operative time, whether to use surgery with surgery, regardless of the fibrin glue. Conclusion: The incidence of colorectal anastomotic leakage with multiple risk factors. Anastomotic leak occurred seriously affect the quality of life of patients and may even be life-threatening, so the risk factors for colorectal cancer postoperative anastomotic fistula master, can effectively improve the therapeutic effect of the surgery, to reduce the incidence of postoperative anastomotic fistula to reduce the suffering of patients and improve the patient's quality of life and improve the prognosis.

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CLC: > Medicine, health > Oncology > Gastrointestinal Cancer > Intestinal neoplasms > Rectal cancer
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