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The Expression of Caveolin-1 in Renal Cell Carcinoma Tissues, Cell Line Kert-3 and Cell Line 293

Author: WangJian
Tutor: XuRenFang
School: Suzhou University
Course: Department of Urology
Keywords: caveolin-1 renal carcinoma RT-PCR
CLC: R737.11
Type: Master's thesis
Year: 2008
Downloads: 21
Quote: 0
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Abstract


Objective To evaluate the relationship between caveolin-1 and renal cell carcinoma by detecting the expression of caveolin-1 mRNA in renal cell carcinoma tissue ,the tissue around tumour ,renal carcinoma cell line kert-3 and renal embryo cell line 293 .Methods Studied the expression of caveolin-1 in renal carcinoma tissue,the tissue around tumour,renal carcinoma cell line kert-3 and renal embryo cell line 293 by the way of RT-PCR,then analyzed the results by comparing its.Results The expression level of caceolin-1 in renal carcinoma cell line kert-3 was higher than in renal embryo cell line293.The expression of caveolin-1 were positive in 50 percent of renal cell carcinoma tissue,however, negative in all of the tissue around tumour.Conclusion There is a close relationship between caveolin-1 and renal cell carcinoma. According the results,the caveolin-1 can be used in the diagnose and treatment of renal cell carcinoma.

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CLC: > Medicine, health > Oncology > Genitourinary tumors > Urinary tumors > Kidney,renal pelvis tumor
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