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The Clinical Effect Observation of D3 Lymph Node Dissection in Radical Gastrectomy for Progressive Gastric Cancer

Author: WeiJiuXing
Tutor: TianDaYu
School: Dalian Medical University
Course: General surgery Sciences
Keywords: Gastric Cancer D3 Lymphadenectomy Lymph node
CLC: R735.2
Type: Master's thesis
Year: 2011
Downloads: 19
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Abstract


Objective: To observe the implementation of D3 dissection for gastric postoperative quality of life, local recurrence rate and survival rate . With D2 dissection for gastric only a comparison group . Explore the D3 dissection surgery applications . Methods: Retrospective analysis from September 2005 to September 2006 in our hospital 139 cases of surgical treatment of gastric cancer data were randomly divided into group A group B , 67 routine gastric D3 dissection (A group ) and 72 patients with gastric cancer D2 dissection for gastric (B group ) , the two cases were treated by surgical staging staging PTNM are all Ⅱ - Ⅲ stage . All statistics were first surgery patients . Two groups were compared operative time , blood loss, hospital stay , postoperative discharge time , number of lymph nodes , local recurrence rate and survival rate of the two groups . Results: ① The two groups of patients in terms of gender , age, pathological differentiation, tumor size , PTNM staging showed no significant difference , P gt; 0.05. ② two groups of patients in the intraoperative blood loss, exhaust , hospitalization time the difference was not statistically significant , P gt; 0.05. Number of lymph nodes there are significant differences . ③ D2 and D3 group after group of 1-2 years, no difference in survival , but the survival rate of 3-5 years there is a difference , D2 group was 65.3%, 59.7%, 38.8%, D3 group , 70.1 %, 65.7 % 53.7% of the comparison between the two P lt; 0.05. Incidence of postoperative complications group D2 and D3 group were 8.6% and 13.5% , no significant difference between the P gt; 0.05, only on the difference in operative time . Conclusion: advanced gastric D3 lymphadenectomy can significantly improve the prognosis does not affect quality of life. Treatment of patients with gastric cancer as advanced stage when the majority , therefore, the low degree of differentiation or deep invasion by tumor size regardless , D3 lymphadenectomy is feasible, than D2 dissection.

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CLC: > Medicine, health > Oncology > Gastrointestinal Cancer > Gastric neoplasms
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