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Study of Perfusion Scan and Postprocessing Technique in Pate Vessels with 64 Slice CT and Its Application in Cerebral Haemodynamic Measurement in Health Adults

Author: WanBing
Tutor: LvFuRong
School: Chongqing Medical University
Course: Medical Imaging and Nuclear Medicine
Keywords: Head and neck blood vessels CT perfusion Delay Time Input artery Normal
CLC: R816
Type: Master's thesis
Year: 2008
Downloads: 139
Quote: 0
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Abstract

The first part of the 64-slice spiral CT cerebral perfusion and vascular imaging of the head and neck joint scanning technology to explore Objective: To investigate the 64-slice spiral CT cerebral perfusion and vascular imaging of the head and neck joint scanning technology. Methods: 84 cases to the head of our hospital enhanced scan and head or neck angiography in patients test results were normal, including the head enhanced 20 patients, head of vascular imaging in 32 patients, in patients with cervical vascular imaging 32 cases. 20 cases of head enhance patient 4ml / s speed and injected in 30 ml of contrast agent (preferably dimension was 370 mgI / ml), 15 ml of physiological saline for Test-bolus scanning, the computation time - density curve (TDC), then the same speed injection 70ml contrast agent (preferably dimension was 370 mgI / ml) in 30 ml of physiological saline for Test-bolus scan, the time density curve with the previous - Comparative; 64 patients with head or neck in patients with vascular imaging, inject 20 ml to 4 ml / s velocity contrast agent (Ultravist 370mgI/ml), 15 ml of normal saline for the Test-bolus scan to calculate the 64 patients with head or neck artery, vein peak time. In: Head enhanced patients with a small dose and high-dose contrast agent vascular peak time difference 8s. Head artery peak time was 19.6 ± 2.6s the venous peak time was 25.7 ± 3.2s; carotid artery peak time of 19 ± 2.8s, the the venous peak time of 26.6 ± 3.1s. Head and neck arteries peak time difference of about 0.6s, head arteries and veins peak time difference of about 6.1s neck arteries and veins peak time difference of about 7.6s. Conclusion: CTP-CTA scan, a small dose of contrast agent through the perfusion scan estimate the peak time of the high-dose contrast agent vascular delay time when large doses of contrast agent angiography small dose of contrast agent vascular peak time plus 8s; head artery carotid artery peak time no significant difference in the joint scan of the head and neck blood vessels, the time to peak of monitoring the head or neck arteries can be; artery peak time for head and neck vein scan, you need based on the delay of about 6s. The second part of multislice spiral CT cerebral perfusion and blood vessels of the head and neck imaging processing technology to explore Objective: To investigate multislice spiral CT cerebral perfusion and vascular imaging of the head and neck post-processing techniques. Methods: to our hospital head CT perfusion imaging in 65 patients, 35 cases of normal, abnormal in 30 cases were bilateral anterior cerebral artery, middle cerebral artery, internal carotid artery as an input reference artery, superior sagittal the sinus vein as the output normal chosen arbitrarily while the determination of brain gray matter, white matter and basal ganglia perfusion parameters, patients with obvious infarct area measurement of infarct area and infarct area contralateral normal brain gray matter and white matter perfusion parameters. Results: the perfusion image post-processing process, 35 cases of normal when the input artery were bilateral anterior cerebral artery, middle cerebral artery internal carotid artery, the output veins are the superior sagittal sinus, the measured normal brain gray matter, white matter and basal ganglia perfusion parameters are the same; 30 cases of patients with obvious infarct zone when the input no significant arterial stenosis, selecting a different input artery, such as bilateral anterior cerebral artery, middle cerebral artery, internal carotid artery, the output vein are superior sagittal sinus, the normal brain gray matter and infarct zone perfusion parameters. Conclusion: Brain perfusion image processing, for normal people, you can select any of the large artery as the input artery; abnormal perfusion area, the vessel did not see significant stenosis, the same can select any large artery as the input artery; unilateral large arteries stenosis to try to choose the normal anterior cerebral artery as the input artery. The blood vessels of the head and neck post-processing to be familiar with a variety of reconstruction and integrated application, in order to better display the lesions of the coronary arteries and do not miss. The third part of the normal adult multi-slice spiral CT perfusion imaging in cerebral hemodynamics quantitative research Objective: To investigate the multi-slice spiral CT perfusion imaging in the quantitative study of normal cerebral hemodynamics value. Methods: 35 cases of normal adults, the routine head CT scan, select the basal ganglia and its adjacent level line CT perfusion imaging, the image obtained by CT perfusion package for post-processing, perfusion images, measure the region of interest blood flow, blood volume, and mean transit time, and its quantitative analysis. Results: normal basal ganglia perfusion above the gray matter, gray matter perfusion higher than the white matter. Normal gray matter mean CBF, CBV and MTT values ??were (52.4 ± 11.7) ml / (100g.min), (2.7 ± 0.6) ml/100g (3.7 ± 1.0) s; white matter (22.3 ± 3.8) ml / (100g.min), (1.4 ± 0.4) ml/100g, (5.1 ± 1.3) s. Conclusion: CT perfusion imaging techniques for the measurement of cerebral hemodynamics indicators provide a new imaging methods, but also provides a new way of thinking for cerebral ischemic disease diagnosis.

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