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β-methyl- naphthoquinone, is the important intermediate for synthesis of anti- bleeding drug K- vitamin , are widely used as feed additives . With the progress of science and technology , the β- methyl naphthoquinone as raw material, can be synthesized in a variety of bioactive pharmaceutical products . For the traditional production process wastewater containing chromium processing complex and difficult problems of environmental pollution , two environmentally friendly synthesis of β- methyl naphthoquinone Production . High concentrations of hydrogen peroxide oxidation naphthoquinone system to take β-methyl- β-methyl naphthalene acetic acid as solvent , OP-10 as the emulsifier , with a mass fraction of 50 % . By orthogonal and single factor experiments, the influence of reaction temperature , reaction time , reaction solvent amount of oxidant ratio of raw materials and dosage of OP-10 , and the ratio of raw materials , such as the impact of process parameters on the reaction results , the optimum reaction conditions : reaction temperature of 100 ° C ; reaction time 4h ; n ( β -MN ) : n ( CH 3 COOH ) 1:16 ; n ( β -MN ) : n (H 2 < / sub> O 2 ) is 1:11 ; OP -10 used in an amount of 0.05 ml / g ( of β -MN ) ; under this condition , the β - methylnaphthalene 96% conversion , β- methyl naphthoquinone yield of 52% . Oxidation of the high concentration of hydrogen peroxide in acetic acid as a solvent , tetrabutylammonium bromide as a phase transfer catalyst , with a mass fraction of 50 % β-methyl - naphthalene system β-methyl- naphthoquinone. By orthogonal and single factor experiments investigated the reaction temperature , reaction time , reaction solvent amount of oxidant ratio of raw materials as well as tetrabutylammonium bromide and the ratio of raw materials , such as the impact of process parameters on the reaction results obtained appropriate reaction conditions : temperature 90 ° C ; reaction time 4H ; n ( β -MN ) : N ( CH 3 COOH ) 1:20 ; in ( H , n ( β -MN ): n 2 O 2 ) 1:11; m (C 16 H 36 BrN): m (β-MN) 1 : 22; under the reaction conditions , the conversion rate of β - methylnaphthalene , was 93.3 % , with a yield of 58.2% of β - methylnaphthalene quinone . IR spectra , LC-MS , and other methods of qualitative identification . Synthesis process by comparing the two , glacial acetic acid as solvent , tetrabutylammonium bromide as a phase transfer catalyst, hydrogen peroxide oxidation of β-methylnaphthalene to β - menaquinone system is a better way .
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