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Objective: 1, as a positive starting point for the different outcomes of cervical ThinPrep cytology test (TCT), evaluate the authenticity and reliability of TCT screening of cervical precancerous lesions in the cervical intraepithelial neoplasia (CIN), explore the TCT reasonably positive starting point in CIN screening; 2, by analyzing the results of different ages and different clinical characteristics crowd TCT explore the clinical value of the TCT. Method: 1, from March 2009 to November 2009 in Taiyuan Maternal and Child Health Hospital gynecological line 271 women with cervical TCT detection and cervical biopsy as the gold standard pathologic examination results, respectively. to ASCUS ASC-H, LSIL and HSIL positive starting point, the evaluation of the authenticity and reliability indicators of TCT in CIN screening by plotting the ROC curve, explore TCT CIN diagnostic tests reasonably positive starting point. 2, March 2009 to August 2009, 1578 cases of women in the Maternal and Child Health Hospital, Taiyuan gynecology outpatient cervical ThinPrep cytology testing, based on the results of analysis of TCT in different age, clinical or without contact bleeding, gynecological check whether the columnar epithelium of the ectopic patients distribution characteristics, so as to explore the value of TCT CIN screening. Results: 1 TCT results set a different starting point for the positive results of the pathological examination as the gold standard for authenticity and reliability evaluation, TCT level diagnosis of CIN. ASC-H is a positive starting point for determination, sensitivity 77.8%, specificity 94.7%, and the misdiagnosis rate was 22.2% misdiagnosis rate was 5.3%. Draw the ROC curve, ASC-H as a positive starting point corresponding to the point closest to the upper left corner of the curve, indicates selection of the ASC-H TCT positive starting point as a critical value of CIN screening, the misdiagnosis rate were low and misdiagnosis. ASC-H is a positive starting point in line with the rate and Kappa values ??were ASC-H highly consistent positive starting point TCT and pathological examination. 2 cervical ThinPrep cytology detected 1578 cases of women, by statistical analysis, ASCUS, ASC-H, LSIL, HSIL differential distribution in each age group; clinical detection have of contact bleeding Group inflammation rate than the non-contact bleeding group, ASCUS, LSIL, ASC-H, HSIL detection rate in the non-contact bleeding group. The the TCT results with the of columnar epithelial ectopic extent there is no statistically significant difference. Conclusion: 1, ASC-H as a clinical diagnostic tests without a positive starting point of contact bleeding women, and clinical diagnostic tests are positive starting point of contact bleeding women with ASCUS as a high level of authenticity of CIN screening and reliability. 2, attention should be paid on the 30-35 years old, 45 to 60-year-old age group, and clinical CIN screening women with a history of contact bleeding.
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